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Page 1
Single-cell Sequencing of Circulating Human Plasmablasts during Staphylococcus aureus Bacteremia.
Kerkman PF, de Vor L, van der Vaart TW, Ten Doesschate T, Muts RM, Depelteau JS, Scheepmaker LM, Ruyken M, de Haas CJC, Aerts PC, Marijnissen RJ, Schuurman J, Beurskens FJ, Gorlani A, Bardoel BW, Rooijakkers SHM. Kerkman PF, et al. Among authors: ruyken m. J Immunol. 2024 Dec 1;213(11):1644-1655. doi: 10.4049/jimmunol.2300858. J Immunol. 2024. PMID: 39451041 Free PMC article.
Agnostic B cell selection approach identifies antibodies against K. pneumoniae that synergistically drive complement activation.
van der Lans SPA, Bardoel BW, Ruyken M, de Haas CJC, Baijens S, Muts RM, Scheepmaker LM, Aerts PC, van 't Wout MFL, Preiner J, Marijnissen RJ, Schuurman J, Beurskens FJ, Kerkman PF, Rooijakkers SHM. van der Lans SPA, et al. Among authors: ruyken m. Nat Commun. 2024 Sep 16;15(1):8100. doi: 10.1038/s41467-024-52372-9. Nat Commun. 2024. PMID: 39285158 Free PMC article.
Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies.
Struijf EM, De la O Becerra KI, Ruyken M, de Haas CJC, van Oosterom F, Siere DY, van Keulen JE, Heesterbeek DAC, Dolk E, Heukers R, Bardoel BW, Gros P, Rooijakkers SHM. Struijf EM, et al. Among authors: ruyken m. J Biol Chem. 2023 Aug;299(8):104956. doi: 10.1016/j.jbc.2023.104956. Epub 2023 Jun 23. J Biol Chem. 2023. PMID: 37356719 Free PMC article.
Multifaceted Activities of Seven Nanobodies against Complement C4b.
De la O Becerra KI, Oosterheert W, van den Bos RM, Xenaki KT, Lorent JH, Ruyken M, Schouten A, Rooijakkers SHM, van Bergen En Henegouwen PMP, Gros P. De la O Becerra KI, et al. Among authors: ruyken m. J Immunol. 2022 May 1;208(9):2207-2219. doi: 10.4049/jimmunol.2100647. Epub 2022 Apr 15. J Immunol. 2022. PMID: 35428691 Free PMC article.
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.
Zwarthoff SA, Widmer K, Kuipers A, Strasser J, Ruyken M, Aerts PC, de Haas CJC, Ugurlar D, den Boer MA, Vidarsson G, van Strijp JAG, Gros P, Parren PWHI, van Kessel KPM, Preiner J, Beurskens FJ, Schuurman J, Ricklin D, Rooijakkers SHM. Zwarthoff SA, et al. Among authors: ruyken m. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2102787118. doi: 10.1073/pnas.2102787118. Proc Natl Acad Sci U S A. 2021. PMID: 34155115 Free PMC article.
36 results