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Page 1
Single-cell Sequencing of Circulating Human Plasmablasts during Staphylococcus aureus Bacteremia.
Kerkman PF, de Vor L, van der Vaart TW, Ten Doesschate T, Muts RM, Depelteau JS, Scheepmaker LM, Ruyken M, de Haas CJC, Aerts PC, Marijnissen RJ, Schuurman J, Beurskens FJ, Gorlani A, Bardoel BW, Rooijakkers SHM. Kerkman PF, et al. Among authors: de haas cjc. J Immunol. 2024 Dec 1;213(11):1644-1655. doi: 10.4049/jimmunol.2300858. J Immunol. 2024. PMID: 39451041 Free PMC article.
Monoclonal antibodies effectively potentiate complement activation and phagocytosis of Staphylococcus epidermidis in neonatal human plasma.
de Vor L, Beudeker CR, Flier A, Scheepmaker LM, Aerts PC, Vijlbrief DC, Bekker MN, Beurskens FJ, van Kessel KPM, de Haas CJC, Rooijakkers SHM, van der Flier M. de Vor L, et al. Among authors: de haas cjc. Front Immunol. 2022 Jul 29;13:933251. doi: 10.3389/fimmu.2022.933251. eCollection 2022. Front Immunol. 2022. PMID: 35967335 Free PMC article.
Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis.
Cruz AR, Bentlage AEH, Blonk R, de Haas CJC, Aerts PC, Scheepmaker LM, Bouwmeester IG, Lux A, van Strijp JAG, Nimmerjahn F, van Kessel KPM, Vidarsson G, Rooijakkers SHM. Cruz AR, et al. Among authors: de haas cjc. J Immunol. 2022 Sep 15;209(6):1146-1155. doi: 10.4049/jimmunol.2200080. Epub 2022 Aug 24. J Immunol. 2022. PMID: 36002230
Agnostic B cell selection approach identifies antibodies against K. pneumoniae that synergistically drive complement activation.
van der Lans SPA, Bardoel BW, Ruyken M, de Haas CJC, Baijens S, Muts RM, Scheepmaker LM, Aerts PC, van 't Wout MFL, Preiner J, Marijnissen RJ, Schuurman J, Beurskens FJ, Kerkman PF, Rooijakkers SHM. van der Lans SPA, et al. Among authors: de haas cjc. Nat Commun. 2024 Sep 16;15(1):8100. doi: 10.1038/s41467-024-52372-9. Nat Commun. 2024. PMID: 39285158 Free PMC article.
Glycan-specific IgM is critical for human immunity to Staphylococcus aureus.
Hendriks A, Kerkman PF, Varkila MRJ, Haitsma Mulier JLG, Ali S, Ten Doesschate T, van der Vaart TW, de Haas CJC, Aerts PC, Cremer OL, Bonten MJM, Nizet V, Liu GY, Codée JDC, Rooijakkers SHM, van Strijp JAG, van Sorge NM. Hendriks A, et al. Among authors: de haas cjc. Cell Rep Med. 2024 Sep 17;5(9):101734. doi: 10.1016/j.xcrm.2024.101734. Cell Rep Med. 2024. PMID: 39293400 Free PMC article.
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation.
Cruz AR, Boer MAD, Strasser J, Zwarthoff SA, Beurskens FJ, de Haas CJC, Aerts PC, Wang G, de Jong RN, Bagnoli F, van Strijp JAG, van Kessel KPM, Schuurman J, Preiner J, Heck AJR, Rooijakkers SHM. Cruz AR, et al. Among authors: de haas cjc, de jong rn. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e2016772118. doi: 10.1073/pnas.2016772118. Proc Natl Acad Sci U S A. 2021. PMID: 33563762 Free PMC article.
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.
Zwarthoff SA, Widmer K, Kuipers A, Strasser J, Ruyken M, Aerts PC, de Haas CJC, Ugurlar D, den Boer MA, Vidarsson G, van Strijp JAG, Gros P, Parren PWHI, van Kessel KPM, Preiner J, Beurskens FJ, Schuurman J, Ricklin D, Rooijakkers SHM. Zwarthoff SA, et al. Among authors: de haas cjc. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2102787118. doi: 10.1073/pnas.2102787118. Proc Natl Acad Sci U S A. 2021. PMID: 34155115 Free PMC article.
78 results