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A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani.
Hayat O, Ullah N, Sirajuddin M, Giardini MA, Nguyen JV, Francisco KR, Liu LJ, Sun YU, Maurya S, McGrosso D, Gonzalez DJ, Caffrey CR, Debnath A, Siqueira-Neto JL. Hayat O, et al. Among authors: caffrey cr. Pathogens. 2022 Nov 26;11(12):1424. doi: 10.3390/pathogens11121424. Pathogens. 2022. PMID: 36558759 Free PMC article.
Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5- a ]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.
Monti L, Liu LJ, Varricchio C, Lucero B, Alle T, Yang W, Bem-Shalom I, Gilson M, Brunden KR, Brancale A, Caffrey CR, Ballatore C. Monti L, et al. Among authors: caffrey cr. bioRxiv [Preprint]. 2023 Mar 11:2023.03.11.532093. doi: 10.1101/2023.03.11.532093. bioRxiv. 2023. Update in: ChemMedChem. 2023 Oct 17;18(20):e202300193. doi: 10.1002/cmdc.202300193 PMID: 36945407 Free PMC article. Updated. Preprint.
Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis.
Spiwoková P, Horn M, Fanfrlík J, Jílková A, Fajtová P, Leontovyč A, Houštecká R, Bieliková L, Brynda J, Chanová M, Mertlíková-Kaiserová H, Caro-Diaz EJE, Almaliti J, El-Sakkary N, Gerwick WH, Caffrey CR, Mareš M. Spiwoková P, et al. Among authors: caffrey cr. ACS Infect Dis. 2024 Jun 14;10(6):1935-1948. doi: 10.1021/acsinfecdis.3c00589. Epub 2024 May 17. ACS Infect Dis. 2024. PMID: 38757505 Free PMC article.
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Alle T, Varricchio C, Yao Y, Lucero B, Nzou G, Demuro S, Muench M, Vuong KD, Oukoloff K, Cornec AS, Francisco KR, Caffrey CR, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Alle T, et al. Among authors: caffrey cr. J Med Chem. 2023 Jan 12;66(1):435-459. doi: 10.1021/acs.jmedchem.2c01411. Epub 2022 Dec 19. J Med Chem. 2023. PMID: 36534051 Free PMC article.
Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5-a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.
Monti L, Liu LJ, Varricchio C, Lucero B, Alle T, Yang W, Bem-Shalom I, Gilson M, Brunden KR, Brancale A, Caffrey CR, Ballatore C. Monti L, et al. Among authors: caffrey cr. ChemMedChem. 2023 Oct 17;18(20):e202300193. doi: 10.1002/cmdc.202300193. Epub 2023 Jul 24. ChemMedChem. 2023. PMID: 37429821 Free PMC article.
177 results