Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth.
Zhang Y, Chen K, Tang SC, Cai Y, Nambu A, See YX, Fu C, Raju A, Lebeau B, Ling Z, Chan JJ, Tay Y, Mutwil M, Lakshmanan M, Tucker-Kellogg G, Chng WJ, Tenen DG, Osato M, Tergaonkar V, Fullwood MJ.
Zhang Y, et al. Among authors: tang sc.
Nat Struct Mol Biol. 2024 Sep 20. doi: 10.1038/s41594-024-01391-7. Online ahead of print.
Nat Struct Mol Biol. 2024.
PMID: 39304765