Veale CGL - Search Results

1

Modulators of the Hop-HSP90 Protein-Protein Interaction Disrupt KSHV Lytic Replication.

Okpara MO, Vaaltyn MC, Watson JL, Alhassan M, Albericio F, de la Torre BG, Clarke DJ, Veale CGL, Edkins AL. Okpara MO, et al. Among authors: veale cgl. ACS Infect Dis. 2024 Nov 8;10(11):3853-3867. doi: 10.1021/acsinfecdis.4c00429. Epub 2024 Oct 30. ACS Infect Dis. 2024. PMID: 39475219 Free PMC article.

2

A native mass spectrometry platform identifies HOP inhibitors that modulate the HSP90-HOP protein-protein interaction.

Veale CGL, Mateos-Jiménez M, Vaaltyn MC, Müller R, Makhubu MP, Alhassan M, de la Torre BG, Albericio F, Mackay CL, Edkins AL, Clarke DJ. Veale CGL, et al. Chem Commun (Camb). 2021 Oct 19;57(83):10919-10922. doi: 10.1039/d1cc04257b. Chem Commun (Camb). 2021. PMID: 34591048

3

Discovery of a small-molecule inhibitor of KSHV lytic replication from the MMV pandemic response box.

Okpara MO, Weaver F, Whitehouse A, Veale CGL, Edkins AL. Okpara MO, et al. Among authors: veale cgl. Antiviral Res. 2024 Oct;230:105990. doi: 10.1016/j.antiviral.2024.105990. Epub 2024 Aug 16. Antiviral Res. 2024. PMID: 39154751 Free article.

4

Native Mass Spectrometry-Guided Screening Identifies Hit Fragments for HOP-HSP90 PPI Inhibition.

Vaaltyn MC, Mateos-Jimenez M, Müller R, Mackay CL, Edkins AL, Clarke DJ, Veale CGL. Vaaltyn MC, et al. Among authors: veale cgl. Chembiochem. 2022 Nov 4;23(21):e202200322. doi: 10.1002/cbic.202200322. Epub 2022 Sep 20. Chembiochem. 2022. PMID: 36017658 Free PMC article.

5

Methionine-Containing Peptides: Avoiding Secondary Reactions in the Final Global Deprotection.

Nandhini KP, Alhassan M, Veale CGL, Albericio F, de la Torre BG. Nandhini KP, et al. Among authors: veale cgl. ACS Omega. 2023 Apr 20;8(17):15631-15637. doi: 10.1021/acsomega.3c01058. eCollection 2023 May 2. ACS Omega. 2023. PMID: 37151509 Free PMC article.

6

A native mass spectrometry approach to qualitatively elucidate interfacial epitopes of transient protein-protein interactions.

Veale CGL, Chakraborty A, Mhlanga R, Albericio F, de la Torre BG, Edkins AL, Clarke DJ. Veale CGL, et al. Chem Commun (Camb). 2024 May 30;60(45):5844-5847. doi: 10.1039/d4cc01251h. Chem Commun (Camb). 2024. PMID: 38752317 Free PMC article.

7

Rationally modified SNX-class Hsp90 inhibitors disrupt extracellular fibronectin assembly without intracellular Hsp90 activity.

Mathenjwa GS, Chakraborty A, Chakraborty A, Muller R, Akerman MP, Bode ML, Edkins AL, Veale CGL. Mathenjwa GS, et al. Among authors: veale cgl. RSC Med Chem. 2024 Sep 2;15(10):3609-15. doi: 10.1039/d4md00501e. Online ahead of print. RSC Med Chem. 2024. PMID: 39290382 Free PMC article.

8

Biological and Medicinal Chemistry in Africa.

Veale CGL, Olomola TO, Chellan P, Edkins AL. Veale CGL, et al. Chembiochem. 2023 Apr 17;24(8):e202300060. doi: 10.1002/cbic.202300060. Epub 2023 Mar 21. Chembiochem. 2023. PMID: 36942876

9

Use of a non-hepatic cell line highlights limitations associated with cell-based assessment of metabolically induced toxicity.

Weyers C, Dingle LMK, Wilhelmi BS, Edkins AL, Veale CGL. Weyers C, et al. Among authors: veale cgl. Drug Chem Toxicol. 2020 Nov;43(6):656-662. doi: 10.1080/01480545.2019.1585869. Epub 2019 Mar 18. Drug Chem Toxicol. 2020. PMID: 30880486

10

Native ion mobility mass spectrometry reveals that small organic acid fragments impart gas-phase stability to carbonic anhydrase II.

Veale CGL, Mateos Jimenez M, Mackay CL, Clarke DJ. Veale CGL, et al. Rapid Commun Mass Spectrom. 2020 Jan 30;34(2):e8570. doi: 10.1002/rcm.8570. Rapid Commun Mass Spectrom. 2020. PMID: 31479545

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