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A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels.
Papa A, Del Rivero Morfin PJ, Chen BX, Yang L, Katchman AN, Zakharov SI, Liu G, Bohnen MS, Zheng V, Katz M, Subramaniam S, Hirsch JA, Weiss S, Dascal N, Karlin A, Pitt GS, Colecraft HM, Ben-Johny M, Marx SO. Papa A, et al. Among authors: yang l. J Clin Invest. 2024 Jan 16;134(5):e176943. doi: 10.1172/JCI176943. J Clin Invest. 2024. PMID: 38227371 Free PMC article.
Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics.
Liu G, Papa A, Katchman AN, Zakharov SI, Roybal D, Hennessey JA, Kushner J, Yang L, Chen BX, Kushnir A, Dangas K, Gygi SP, Pitt GS, Colecraft HM, Ben-Johny M, Kalocsay M, Marx SO. Liu G, et al. Among authors: yang l. Nature. 2020 Jan;577(7792):695-700. doi: 10.1038/s41586-020-1947-z. Epub 2020 Jan 22. Nature. 2020. PMID: 31969708 Free PMC article.
Adrenergic CaV1.2 Activation via Rad Phosphorylation Converges at α1C I-II Loop.
Papa A, Kushner J, Hennessey JA, Katchman AN, Zakharov SI, Chen BX, Yang L, Lu R, Leong S, Diaz J, Liu G, Roybal D, Liao X, Del Rivero Morfin PJ, Colecraft HM, Pitt GS, Clarke O, Topkara V, Ben-Johny M, Marx SO. Papa A, et al. Among authors: yang l. Circ Res. 2021 Jan 8;128(1):76-88. doi: 10.1161/CIRCRESAHA.120.317839. Epub 2020 Oct 22. Circ Res. 2021. PMID: 33086983 Free PMC article.
A Genetically Encoded Actuator Selectively Boosts L-type Calcium Channels in Diverse Physiological Settings.
Del Rivero Morfin PJ, Chavez DS, Jayaraman S, Yang L, Kochiss AL, Colecraft HM, Liu XS, Marx SO, Rajadhyaksha AM, Ben-Johny M. Del Rivero Morfin PJ, et al. Among authors: yang l. bioRxiv [Preprint]. 2023 Sep 23:2023.09.22.558856. doi: 10.1101/2023.09.22.558856. bioRxiv. 2023. Update in: Sci Adv. 2024 Nov;10(44):eadq3374. doi: 10.1126/sciadv.adq3374 PMID: 37790372 Free PMC article. Updated. Preprint.
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