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Temporal recording of mammalian development and precancer.
Islam M, Yang Y, Simmons AJ, Shah VM, Musale KP, Xu Y, Tasneem N, Chen Z, Trinh LT, Molina P, Ramirez-Solano MA, Sadien ID, Dou J, Rolong A, Chen K, Magnuson MA, Rathmell JC, Macara IG, Winton DJ, Liu Q, Zafar H, Kalhor R, Church GM, Shrubsole MJ, Coffey RJ, Lau KS. Islam M, et al. Among authors: chen z, chen k. Nature. 2024 Oct;634(8036):1187-1195. doi: 10.1038/s41586-024-07954-4. Epub 2024 Oct 30. Nature. 2024. PMID: 39478207 Free PMC article.
Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors.
Heiser CN, Simmons AJ, Revetta F, McKinley ET, Ramirez-Solano MA, Wang J, Kaur H, Shao J, Ayers GD, Wang Y, Glass SE, Tasneem N, Chen Z, Qin Y, Kim W, Rolong A, Chen B, Vega PN, Drewes JL, Markham NO, Saleh N, Nikolos F, Vandekar S, Jones AL, Washington MK, Roland JT, Chan KS, Schürpf T, Sears CL, Liu Q, Shrubsole MJ, Coffey RJ, Lau KS. Heiser CN, et al. Among authors: chen z, chen b. Cell. 2023 Dec 7;186(25):5620-5637.e16. doi: 10.1016/j.cell.2023.11.006. Cell. 2023. PMID: 38065082 Free PMC article.
The Hallmarks of Precancer.
Stangis MM, Chen Z, Min J, Glass SE, Jackson JO, Radyk MD, Hoi XP, Brennen WN, Yu M, Dinh HQ, Coffey RJ, Shrubsole MJ, Chan KS, Grady WM, Yegnasubramanian S, Lyssiotis CA, Maitra A, Halberg RB, Dey N, Lau KS. Stangis MM, et al. Among authors: chen z. Cancer Discov. 2024 Apr 4;14(4):683-689. doi: 10.1158/2159-8290.CD-23-1550. Cancer Discov. 2024. PMID: 38571435
A contamination focused approach for optimizing the single-cell RNA-seq experiment.
Arceneaux D, Chen Z, Simmons AJ, Heiser CN, Southard-Smith AN, Brenan MJ, Yang Y, Chen B, Xu Y, Choi E, Campbell JD, Liu Q, Lau KS. Arceneaux D, et al. Among authors: chen z, chen b. iScience. 2023 Jun 29;26(7):107242. doi: 10.1016/j.isci.2023.107242. eCollection 2023 Jul 21. iScience. 2023. PMID: 37496679 Free PMC article.
MTGR1 is required to maintain small intestinal stem cell populations.
Short SP, Brown RE, Chen Z, Pilat JM, McElligott BA, Meenderink LM, Bickart AC, Blunt KM, Jacobse J, Wang J, Simmons AJ, Xu Y, Yang Y, Parang B, Choksi YA, Goettel JA, Lau KS, Hiebert SW, Williams CS. Short SP, et al. Among authors: chen z. Cell Death Differ. 2024 Sep;31(9):1170-1183. doi: 10.1038/s41418-024-01346-x. Epub 2024 Jul 25. Cell Death Differ. 2024. PMID: 39048708 Free PMC article.
Oncogenic K-Ras suppresses global miRNA function.
Shui B, Beyett TS, Chen Z, Li X, La Rocca G, Gazlay WM, Eck MJ, Lau KS, Ventura A, Haigis KM. Shui B, et al. Among authors: chen z. Mol Cell. 2023 Jul 20;83(14):2509-2523.e13. doi: 10.1016/j.molcel.2023.06.008. Epub 2023 Jul 3. Mol Cell. 2023. PMID: 37402366 Free PMC article.
MTGR1 is required to maintain small intestinal stem cell populations.
Williams C, Brown R, Zhao Y, Wang J, Chen Z, Blunt K, Pilat J, Parang B, Choksi Y, Lau K, Hiebert S, Short S, Jacobse J, Xu Y, Yang Y, Goettel J. Williams C, et al. Among authors: chen z. Res Sq [Preprint]. 2023 Sep 21:rs.3.rs-3315071. doi: 10.21203/rs.3.rs-3315071/v1. Res Sq. 2023. Update in: Cell Death Differ. 2024 Sep;31(9):1170-1183. doi: 10.1038/s41418-024-01346-x PMID: 37790452 Free PMC article. Updated. Preprint.
Programming bacteria for multiplexed DNA detection.
Cheng YY, Chen Z, Cao X, Ross TD, Falbel TG, Burton BM, Venturelli OS. Cheng YY, et al. Among authors: chen z. Nat Commun. 2023 Apr 10;14(1):2001. doi: 10.1038/s41467-023-37582-x. Nat Commun. 2023. PMID: 37037805 Free PMC article.
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