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Longitudinal analysis of the gut microbiota during anti-PD-1 therapy reveals stable microbial features of response in melanoma patients.
Macandog ADG, Catozzi C, Capone M, Nabinejad A, Nanaware PP, Liu S, Vinjamuri S, Stunnenberg JA, Galiè S, Jodice MG, Montani F, Armanini F, Cassano E, Madonna G, Mallardo D, Mazzi B, Pece S, Tagliamonte M, Vanella V, Barberis M, Ferrucci PF, Blank CU, Bouvier M, Andrews MC, Xu X, Santambrogio L, Segata N, Buonaguro L, Cocorocchio E, Ascierto PA, Manzo T, Nezi L. Macandog ADG, et al. Among authors: pece s. Cell Host Microbe. 2024 Nov 13;32(11):2004-2018.e9. doi: 10.1016/j.chom.2024.10.006. Epub 2024 Oct 30. Cell Host Microbe. 2024. PMID: 39481388 Free PMC article.
Actionable Genetic Screens Unveil Targeting of AURKA, MEK, and Fatty Acid Metabolism as an Alternative Therapeutic Approach for Advanced Melanoma.
Marocchi F, Palluzzi F, Nicoli P, Melixetian M, Lovati G, Bertalot G, Pece S, Ferrucci PF, Bossi D, Lanfrancone L. Marocchi F, et al. Among authors: pece s. J Invest Dermatol. 2023 Oct;143(10):1993-2006.e10. doi: 10.1016/j.jid.2023.03.1665. Epub 2023 Mar 31. J Invest Dermatol. 2023. PMID: 37003468 Free article.
Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition.
Cazzoli R, Romeo F, Pallavicini I, Peri S, Romanenghi M, Pérez-Valencia JA, Hagag E, Ferrucci F, Elgendy M, Vittorio O, Pece S, Foiani M, Westermarck J, Minucci S. Cazzoli R, et al. Among authors: pece s. Cell Rep. 2023 Jun 27;42(6):112616. doi: 10.1016/j.celrep.2023.112616. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37289585 Free article.
WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumors.
Mulè P, Fernandez-Perez D, Amato S, Manganaro D, Oldani P, Brandini S, Diaferia G, Cuomo A, Recordati C, Soriani C, Dondi A, Zanotti M, Rustichelli S, Bisso A, Pece S, Rodighiero S, Natoli G, Amati B, Ferrari KJ, Chiacchiera F, Pasini D. Mulè P, et al. Among authors: pece s. Gastroenterology. 2024 Oct;167(5):903-918. doi: 10.1053/j.gastro.2024.06.029. Epub 2024 Jul 5. Gastroenterology. 2024. PMID: 38971196 Free article.
The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells.
Talia M, Cirillo F, Spinelli A, Zicarelli A, Scordamaglia D, Muglia L, De Rosis S, Rigiracciolo DC, Filippelli G, Perrotta ID, Davoli M, De Rosa R, Macirella R, Brunelli E, Miglietta AM, Nardo B, Tosoni D, Pece S, De Francesco EM, Belfiore A, Maggiolini M, Lappano R. Talia M, et al. Among authors: pece s. J Exp Clin Cancer Res. 2023 Jul 12;42(1):164. doi: 10.1186/s13046-023-02747-5. J Exp Clin Cancer Res. 2023. PMID: 37434266 Free PMC article.
Loss of NUMB drives aggressive bladder cancer via a RHOA/ROCK/YAP signaling axis.
Tucci FA, Pennisi R, Rigiracciolo DC, Filippone MG, Bonfanti R, Romeo F, Freddi S, Guerrera E, Soriani C, Rodighiero S, Gunby RH, Jodice G, Sanguedolce F, Renne G, Fusco N, Di Fiore PP, Pruneri G, Bertalot G, Musi G, Vago G, Tosoni D, Pece S. Tucci FA, et al. Among authors: pece s. Nat Commun. 2024 Dec 3;15(1):10378. doi: 10.1038/s41467-024-54246-6. Nat Commun. 2024. PMID: 39627202 Free PMC article.
Intracellular Osteopontin Promotes the Release of TNFα by Mast Cells to Restrain Neuroendocrine Prostate Cancer.
Sulsenti R, Scialpi GB, Frossi B, Botti L, Ferri R, Tripodi I, Piva A, Sangaletti S, Pernici D, Cancila V, Romeo F, Chiodoni C, Lecis D, Bianchi F, Fischetti I, Enriquez C, Crivelli F, Bregni M, Renne G, Pece S, Tripodo C, Pucillo CE, Colombo MP, Jachetti E. Sulsenti R, et al. Among authors: pece s. Cancer Immunol Res. 2024 Sep 3;12(9):1147-1169. doi: 10.1158/2326-6066.CIR-23-0792. Cancer Immunol Res. 2024. PMID: 38869181 Free PMC article.
p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.
Salemme V, Vedelago M, Sarcinella A, Moietta F, Piccolantonio A, Moiso E, Centonze G, Manco M, Guala A, Lamolinara A, Angelini C, Morellato A, Natalini D, Calogero R, Incarnato D, Oliviero S, Conti L, Iezzi M, Tosoni D, Bertalot G, Freddi S, Tucci FA, De Sanctis F, Frusteri C, Ugel S, Bronte V, Cavallo F, Provero P, Gai M, Taverna D, Turco E, Pece S, Defilippi P. Salemme V, et al. Among authors: pece s. Nat Commun. 2023 May 11;14(1):2350. doi: 10.1038/s41467-023-37824-y. Nat Commun. 2023. PMID: 37169737 Free PMC article.
TFEB and TFE3 drive kidney cystogenesis and tumorigenesis.
Di Malta C, Zampelli A, Granieri L, Vilardo C, De Cegli R, Cinque L, Nusco E, Pece S, Tosoni D, Sanguedolce F, Sorrentino NC, Merino MJ, Nielsen D, Srinivasan R, Ball MW, Ricketts CJ, Vocke CD, Lang M, Karim B, Lanfrancone L, Schmidt LS, Linehan WM, Ballabio A. Di Malta C, et al. Among authors: pece s. EMBO Mol Med. 2023 May 8;15(5):e16877. doi: 10.15252/emmm.202216877. Epub 2023 Mar 29. EMBO Mol Med. 2023. PMID: 36987696 Free PMC article.
84 results