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Maternal ingestion of cannabidiol (CBD) in mice leads to sex-dependent changes in memory, anxiety, and metabolism in the adult offspring, and causes a decrease in survival to weaning age.
Compagno MK, Silver CR, Cox-Holmes A, Basso KB, Bishop C, Bernstein AM, Carley A, Cazorla J, Claydon J, Crane A, Crespi C, Curley E, Dolezel T, Franck E, Heiden K, Huffstetler CM, Loeven AM, May CA, Maykut N, Narvarez A, Pacheco FA, Turner O, Fadool DA. Compagno MK, et al. Among authors: maykut n. Pharmacol Biochem Behav. 2024 Oct 29;247:173902. doi: 10.1016/j.pbb.2024.173902. Online ahead of print. Pharmacol Biochem Behav. 2024. PMID: 39481653 Free article.
Single cannabidiol administration affects anxiety-, obsessive compulsive-, object memory-, and attention-like behaviors in mice in a sex and concentration dependent manner.
Huffstetler CM, Cochran B, May CA, Maykut N, Silver CR, Cedeno C, Franck E, Cox A, Fadool DA. Huffstetler CM, et al. Among authors: maykut n. Pharmacol Biochem Behav. 2023 Jan;222:173498. doi: 10.1016/j.pbb.2022.173498. Epub 2022 Nov 29. Pharmacol Biochem Behav. 2023. PMID: 36455670 Free article.