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Page 1
Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
Miranda-Cervantes A, Fritzen AM, Raun SH, Hodek O, Møller LLV, Johann K, Deisen L, Gregorevic P, Gudiksen A, Artati A, Adamski J, Andersen NR, Sigvardsen CM, Carl CS, Voldstedlund CT, Kjøbsted R, Hauck SM, Schjerling P, Jensen TE, Cebrian-Serrano A, Jähnert M, Gottmann P, Burtscher I, Lickert H, Pilegaard H, Schürmann A, Tschöp MH, Moritz T, Müller TD, Sylow L, Kiens B, Richter EA, Kleinert M. Miranda-Cervantes A, et al. Among authors: gudiksen a. Nat Commun. 2025 Jan 2;16(1):345. doi: 10.1038/s41467-024-55036-w. Nat Commun. 2025. PMID: 39746949 Free PMC article.
Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise.
Kristensen JM, Kjøbsted R, Larsen TJ, Carl CS, Hingst JR, Onslev J, Birk JB, Thorup A, Steenberg DE, Knudsen JR, Henriksen NS, Needham EJ, Halling JF, Gudiksen A, Rundsten CF, Hanghøj KE, Stinson SE, Hoier B, Hansen CC, Jensen TE, Hellsten Y, Pilegaard H, Grarup N, Olesen J, Humphrey SJ, James DE, Pedersen ML, Richter EA, Hansen T, Jørgensen ME, Wojtaszewski JFP. Kristensen JM, et al. Among authors: gudiksen a. Nat Metab. 2024 Dec;6(12):2254-2266. doi: 10.1038/s42255-024-01153-1. Epub 2024 Oct 31. Nat Metab. 2024. PMID: 39482542 Free PMC article.
Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes.
Maurer J, Zhao X, Irmler M, Gudiksen A, Pilmark NS, Li Q, Goj T, Beckers J, Hrabě de Angelis M, Birkenfeld AL, Peter A, Lehmann R, Pilegaard H, Karstoft K, Xu G, Weigert C. Maurer J, et al. Among authors: gudiksen a. Am J Physiol Cell Physiol. 2023 Oct 1;325(4):C1131-C1143. doi: 10.1152/ajpcell.00186.2023. Epub 2023 Sep 11. Am J Physiol Cell Physiol. 2023. PMID: 37694284 Free PMC article.
GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans.
Plomgaard P, Hansen JS, Townsend LK, Gudiksen A, Secher NH, Clemmesen JO, Støving RK, Goetze JP, Wright DC, Pilegaard H. Plomgaard P, et al. Among authors: gudiksen a. Front Endocrinol (Lausanne). 2022 Dec 5;13:1037948. doi: 10.3389/fendo.2022.1037948. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36545337 Free PMC article.
Muscle PGC-1α modulates hepatic mitophagy regulation during aging.
Christensen NM, Ringholm S, Buch BT, Gudiksen A, Halling JF, Pilegaard H. Christensen NM, et al. Among authors: gudiksen a. Exp Gerontol. 2023 Feb;172:112046. doi: 10.1016/j.exger.2022.112046. Epub 2022 Dec 13. Exp Gerontol. 2023. PMID: 36521568 Free article.
Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2 × 2 factorial, randomised, crossover study in human individuals.
Hjelholt AJ, Charidemou E, Griffin JL, Pedersen SB, Gudiksen A, Pilegaard H, Jessen N, Møller N, Jørgensen JOL. Hjelholt AJ, et al. Among authors: gudiksen a. Diabetologia. 2020 Dec;63(12):2641-2653. doi: 10.1007/s00125-020-05262-w. Epub 2020 Sep 18. Diabetologia. 2020. PMID: 32945898 Clinical Trial.
32 results