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Page 1
Metabolic programs drive function of therapeutic NK cells in hypoxic tumor environments.
Kennedy PR, Arvindam US, Phung SK, Ettestad B, Feng X, Li Y, Kile QM, Hinderlie P, Khaw M, Huang RS, Kaufman M, Puchalska P, Russell A, Butler J, Abbott L, McClure P, Luo X, Lu QT, Blazar BR, Crawford PA, Lim J, Miller JS, Felices M. Kennedy PR, et al. Among authors: crawford pa. Sci Adv. 2024 Nov;10(44):eadn1849. doi: 10.1126/sciadv.adn1849. Epub 2024 Oct 30. Sci Adv. 2024. PMID: 39475618 Free PMC article.
Ketogenesis protects against MASLD-MASH progression through fat oxidation-independent mechanisms.
Queathem ED, Stagg DB, Nelson AB, Chaves AB, Crown SB, Fulghum K, d'Avignon DA, Ryder JR, Bolan PJ, Hayir A, Gillingham JR, Jannatpour S, Rome FI, Williams AS, Muoio DM, Ikramuddin S, Hughey C, Puchalska P, Crawford PA. Queathem ED, et al. Among authors: crawford pa. bioRxiv [Preprint]. 2024 Oct 17:2024.10.17.618895. doi: 10.1101/2024.10.17.618895. bioRxiv. 2024. PMID: 39464122 Free PMC article. Preprint.
Gender-based heterogeneity of FAHFAs in trained runners.
Nelson AB, Chow LS, Dengel DR, Pan M, Hughey CC, Han X, Puchalska P, Crawford PA. Nelson AB, et al. Among authors: crawford pa. PLoS One. 2024 May 6;19(5):e0300037. doi: 10.1371/journal.pone.0300037. eCollection 2024. PLoS One. 2024. PMID: 38709787 Free PMC article.
Metabolic Messengers: ketone bodies.
Nelson AB, Queathem ED, Puchalska P, Crawford PA. Nelson AB, et al. Among authors: crawford pa. Nat Metab. 2023 Dec;5(12):2062-2074. doi: 10.1038/s42255-023-00935-3. Epub 2023 Dec 13. Nat Metab. 2023. PMID: 38092961 Review.
Ketone bodies in right ventricular failure: A unique therapeutic opportunity.
Blake M, Puchalska P, Kazmirczak F, Blake J, Moon R, Thenappan T, Crawford PA, Prins KW. Blake M, et al. Among authors: crawford pa. Heliyon. 2023 Nov 15;9(11):e22227. doi: 10.1016/j.heliyon.2023.e22227. eCollection 2023 Nov. Heliyon. 2023. PMID: 38058654 Free PMC article.
A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: crawford pa. bioRxiv [Preprint]. 2024 May 13:2023.11.02.565382. doi: 10.1101/2023.11.02.565382. bioRxiv. 2024. PMID: 37961209 Free PMC article. Preprint.
Ketone ester administration improves glycemia in obese mice.
Tabatabaei Dakhili SA, Yang K, Locatelli CAA, Saed CT, Greenwell AA, Chan JSF, Chahade JJ, Scharff J, Al-Imarah S, Eaton F, Crawford PA, Gopal K, Mulvihill EE, Ussher JR. Tabatabaei Dakhili SA, et al. Among authors: crawford pa. Am J Physiol Cell Physiol. 2023 Sep 1;325(3):C750-C757. doi: 10.1152/ajpcell.00300.2023. Epub 2023 Aug 14. Am J Physiol Cell Physiol. 2023. PMID: 37575059 Free article.
Ketolysis drives CD8+ T cell effector function through effects on histone acetylation.
Luda KM, Longo J, Kitchen-Goosen SM, Duimstra LR, Ma EH, Watson MJ, Oswald BM, Fu Z, Madaj Z, Kupai A, Dickson BM, DeCamp LM, Dahabieh MS, Compton SE, Teis R, Kaymak I, Lau KH, Kelly DP, Puchalska P, Williams KS, Krawczyk CM, Lévesque D, Boisvert FM, Sheldon RD, Rothbart SB, Crawford PA, Jones RG. Luda KM, et al. Among authors: crawford pa. Immunity. 2023 Sep 12;56(9):2021-2035.e8. doi: 10.1016/j.immuni.2023.07.002. Epub 2023 Jul 28. Immunity. 2023. PMID: 37516105 Free PMC article.
101 results