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Page 1
Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malaria.
Marques-da-Silva C, Schmidt-Silva C, Bowers C, Charles-Chess E, Shiau JC, Park ES, Yuan Z, Kim BH, Kyle DE, Harty JT, MacMicking JD, Kurup SP. Marques-da-Silva C, et al. Among authors: kyle de. bioRxiv [Preprint]. 2024 Oct 24:2024.10.22.619707. doi: 10.1101/2024.10.22.619707. bioRxiv. 2024. PMID: 39484443 Free PMC article. Preprint.
Optimization of diastereomeric dihydropyridines as antimalarials.
Van Horn KS, Zhao Y, Parvatkar PT, Maier J, Mutka T, Lacrue A, Brockmeier F, Ebert D, Wu W, Casandra DR, Namelikonda N, Yacoub J, Sigal M, Knapp S, Floyd D, Waterson D, Burrows JN, Duffy J, DeRisi JL, Kyle DE, Guy RK, Manetsch R. Van Horn KS, et al. Among authors: kyle de. Eur J Med Chem. 2024 Sep 5;275:116599. doi: 10.1016/j.ejmech.2024.116599. Epub 2024 Jun 18. Eur J Med Chem. 2024. PMID: 38909569
Extended blood stage sensitivity profiles of Plasmodium cynomolgi to doxycycline and tafenoquine, as a model for Plasmodium vivax.
Christensen P, Cinzah R, Suwanarusk R, Chua ACY, Kaneko O, Kyle DE, Aung HL, Matheson J, Bifani P, Rénia L, Cook GM, Snounou G, Russell B. Christensen P, et al. Among authors: kyle de. Antimicrob Agents Chemother. 2024 May 2;68(5):e0028024. doi: 10.1128/aac.00280-24. Epub 2024 Apr 8. Antimicrob Agents Chemother. 2024. PMID: 38587391 Free PMC article.
Corrigendum: Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes.
Ferrins L, Buskes MJ, Kapteyn MM, Engels HN, Enos SE, Lu C, Klug DM, Singh B, Quotadamo A, Bachovchin K, Tear WF, Spaulding AE, Forbes KC, Bag S, Rivers M, LeBlanc C, Burchfield E, Armand JR, Diaz-Gonzalez R, Ceballos-Perez G, García-Hernández R, Pérez-Moreno G, Bosch-Navarrete C, Gómez-Liñán C, Ruiz-Pérez LM, Gamarro F, González-Pacanowska D, Navarro M, Mensa-Wilmot K, Pollastri MP, Kyle DE, Rice CA. Ferrins L, et al. Among authors: kyle de. Front Microbiol. 2023 Oct 25;14:1304196. doi: 10.3389/fmicb.2023.1304196. eCollection 2023. Front Microbiol. 2023. PMID: 37954236 Free PMC article.
Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases.
Kassu M, Parvatkar PT, Milanes J, Monaghan NP, Kim C, Dowgiallo M, Zhao Y, Asakawa AH, Huang L, Wagner A, Miller B, Carter K, Barrett KF, Tillery LM, Barrett LK, Phan IQ, Subramanian S, Myler PJ, Van Voorhis WC, Leahy JW, Rice CA, Kyle DE, Morris J, Manetsch R. Kassu M, et al. Among authors: kyle de. ACS Infect Dis. 2023 Nov 10;9(11):2190-2201. doi: 10.1021/acsinfecdis.3c00284. Epub 2023 Oct 11. ACS Infect Dis. 2023. PMID: 37820055 Free PMC article.
226 results