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101 results

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Page 1
A peptide encoded by upstream open reading frame of MYC binds to tropomyosin receptor kinase B and promotes glioblastoma growth in mice.
Li F, Yang K, Gao X, Zhang M, Gu D, Wu X, Lu C, Wu Q, Dixit D, Gimple RC, You Y, Mack SC, Shi Y, Kang T, Agnihotri SA, Taylor MD, Rich JN, Zhang N, Wang X. Li F, et al. Among authors: mack sc. Sci Transl Med. 2024 Oct 2;16(767):eadk9524. doi: 10.1126/scitranslmed.adk9524. Epub 2024 Oct 2. Sci Transl Med. 2024. PMID: 39356747
Dominant Malignant Clones Leverage Lineage Restricted Epigenomic Programs to Drive Ependymoma Development.
Kardian A, Sun H, Ippagunta S, Laboe N, Chen HC, Emanus E, Varadharajan S, Zheng T, Holcomb B, Connelly P, Connelly JP, Wang M, Lowe K, Pruett-Miller SM, Bertrand KC, Deneen B, Mack SC. Kardian A, et al. Among authors: mack sc. bioRxiv [Preprint]. 2024 Aug 15:2024.08.12.607603. doi: 10.1101/2024.08.12.607603. bioRxiv. 2024. PMID: 39211123 Free PMC article. Preprint.
Histone serotonylation regulates ependymoma tumorigenesis.
Chen HC, He P, McDonald M, Williamson MR, Varadharajan S, Lozzi B, Woo J, Choi DJ, Sardar D, Huang-Hobbs E, Sun H, Ippagunta SM, Jain A, Rao G, Merchant TE, Ellison DW, Noebels JL, Bertrand KC, Mack SC, Deneen B. Chen HC, et al. Among authors: mack sc. Nature. 2024 Aug;632(8026):903-910. doi: 10.1038/s41586-024-07751-z. Epub 2024 Jul 31. Nature. 2024. PMID: 39085609
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages.
Li D, Wang X, Chen K, Shan D, Cui G, Yuan W, Lin Q, Gimple RC, Dixit D, Lu C, Gu D, You H, Gao J, Li Y, Kang T, Yang J, Yu H, Song K, Shi Z, Fan X, Wu Q, Gao W, Zhu Z, Man J, Wang Q, Lin F, Tao W, Mack SC, Chen Y, Zhang J, Li C, Zhang N, You Y, Qian X, Yang K, Rich JN, Zhang Q, Wang X. Li D, et al. Among authors: mack sc. Cell Death Differ. 2024 Jun;31(6):738-752. doi: 10.1038/s41418-024-01292-8. Epub 2024 Apr 9. Cell Death Differ. 2024. PMID: 38594444
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
Casillo SM, Gatesman TA, Chilukuri A, Varadharajan S, Johnson BJ, David Premkumar DR, Jane EP, Plute TJ, Koncar RF, Stanton AJ, Biagi-Junior CAO, Barber CS, Halbert ME, Golbourn BJ, Halligan K, Cruz AF, Mansi NM, Cheney A, Mullett SJ, Land CV, Perez JL, Myers MI, Agrawal N, Michel JJ, Chang YF, Vaske OM, MichaelRaj A, Lieberman FS, Felker J, Shiva S, Bertrand KC, Amankulor N, Hadjipanayis CG, Abdullah KG, Zinn PO, Friedlander RM, Abel TJ, Nazarian J, Venneti S, Filbin MG, Gelhaus SL, Mack SC, Pollack IF, Agnihotri S. Casillo SM, et al. Among authors: mack sc. Cell Rep. 2024 Jan 23;43(1):113557. doi: 10.1016/j.celrep.2023.113557. Epub 2023 Dec 18. Cell Rep. 2024. PMID: 38113141 Free article.
OpenPBTA: The Open Pediatric Brain Tumor Atlas.
Shapiro JA, Gaonkar KS, Spielman SJ, Savonen CL, Bethell CJ, Jin R, Rathi KS, Zhu Y, Egolf LE, Farrow BK, Miller DP, Yang Y, Koganti T, Noureen N, Koptyra MP, Duong N, Santi M, Kim J, Robins S, Storm PB, Mack SC, Lilly JV, Xie HM, Jain P, Raman P, Rood BR, Lulla RR, Nazarian J, Kraya AA, Vaksman Z, Heath AP, Kline C, Scolaro L, Viaene AN, Huang X, Way GP, Foltz SM, Zhang B, Poetsch AR, Mueller S, Ennis BM, Prados M, Diskin SJ, Zheng S, Guo Y, Kannan S, Waanders AJ, Margol AS, Kim MC, Hanson D, Van Kuren N, Wong J, Kaufman RS, Coleman N, Blackden C, Cole KA, Mason JL, Madsen PJ, Koschmann CJ, Stewart DR, Wafula E, Brown MA, Resnick AC, Greene CS, Rokita JL, Taroni JN; Children’s Brain Tumor Network; Pacific Pediatric Neuro-Oncology Consortium. Shapiro JA, et al. Among authors: mack sc. Cell Genom. 2023 May 31;3(7):100340. doi: 10.1016/j.xgen.2023.100340. eCollection 2023 Jul 12. Cell Genom. 2023. PMID: 37492101 Free PMC article.
Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages.
Yuan W, Zhang Q, Gu D, Lu C, Dixit D, Gimple RC, Gao Y, Gao J, Li D, Shan D, Hu L, Li L, Li Y, Ci S, You H, Yan L, Chen K, Zhao N, Xu C, Lan J, Liu D, Zhang J, Shi Z, Wu Q, Yang K, Zhao L, Qiu Z, Lv D, Gao W, Yang H, Lin F, Wang Q, Man J, Li C, Tao W, Agnihotri S, Qian X, Mack SC, Zhang N, You Y, Rich JN, Sun G, Wang X. Yuan W, et al. Among authors: mack sc. Clin Cancer Res. 2023 Sep 15;29(18):3779-3792. doi: 10.1158/1078-0432.CCR-22-3273. Clin Cancer Res. 2023. PMID: 37439870
101 results