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Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole.
Corrales J, Ramos-Alonso L, González-Sabín J, Ríos-Lombardía N, Trevijano-Contador N, Engen Berg H, Sved Skottvoll F, Moris F, Zaragoza O, Chymkowitch P, Garcia I, Enserink JM. Corrales J, et al. Among authors: zaragoza o. Microbiol Spectr. 2024 Feb 6;12(2):e0259423. doi: 10.1128/spectrum.02594-23. Epub 2024 Jan 17. Microbiol Spectr. 2024. PMID: 38230926 Free PMC article.
The production of reactive oxygen species is a universal action mechanism of Amphotericin B against pathogenic yeasts and contributes to the fungicidal effect of this drug.
Mesa-Arango AC, Trevijano-Contador N, Román E, Sánchez-Fresneda R, Casas C, Herrero E, Argüelles JC, Pla J, Cuenca-Estrella M, Zaragoza O. Mesa-Arango AC, et al. Among authors: zaragoza o. Antimicrob Agents Chemother. 2014 Nov;58(11):6627-38. doi: 10.1128/AAC.03570-14. Epub 2014 Aug 25. Antimicrob Agents Chemother. 2014. PMID: 25155595 Free PMC article.
Fungal morphogenetic changes inside the mammalian host.
Trevijano-Contador N, Rueda C, Zaragoza O. Trevijano-Contador N, et al. Among authors: zaragoza o. Semin Cell Dev Biol. 2016 Sep;57:100-109. doi: 10.1016/j.semcdb.2016.04.008. Epub 2016 Apr 19. Semin Cell Dev Biol. 2016. PMID: 27101887 Review.
Cryptococcal Titan Cells: When Yeast Cells Are All Grown up.
García-Rodas R, de Oliveira HC, Trevijano-Contador N, Zaragoza O. García-Rodas R, et al. Among authors: zaragoza o. Curr Top Microbiol Immunol. 2019;422:101-120. doi: 10.1007/82_2018_145. Curr Top Microbiol Immunol. 2019. PMID: 30406867 Review.
134 results