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Cancer-associated fibroblasts shape early myeloid cell response to chemotherapy-induced immunogenic signals in next generation tumor organoid cultures.
Kabiljo J, Theophil A, Homola J, Renner AF, Stürzenbecher N, Ammon D, Zirnbauer R, Stang S, Tran L, Laengle J, Kulu A, Chen A, Fabits M, Atanasova VS, Pusch O, Weninger W, Walczak H, Herndler Brandstetter D, Egger G, Dolznig H, Kusienicka A, Farlik M, Bergmann M. Kabiljo J, et al. Among authors: dolznig h. J Immunother Cancer. 2024 Nov 4;12(11):e009494. doi: 10.1136/jitc-2024-009494. J Immunother Cancer. 2024. PMID: 39500527 Free PMC article.
Mimicking Tumor Cell Heterogeneity of Colorectal Cancer in a Patient-derived Organoid-Fibroblast Model.
Atanasova VS, de Jesus Cardona C, Hejret V, Tiefenbacher A, Mair T, Tran L, Pfneissl J, Draganić K, Binder C, Kabiljo J, Clement J, Woeran K, Neudert B, Wohlhaupter S, Haase A, Domazet S, Hengstschläger M, Mitterhauser M, Müllauer L, Tichý B, Bergmann M, Schweikert G, Hartl M, Dolznig H, Egger G. Atanasova VS, et al. Among authors: dolznig h. Cell Mol Gastroenterol Hepatol. 2023;15(6):1391-1419. doi: 10.1016/j.jcmgh.2023.02.014. Epub 2023 Mar 2. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36868311 Free PMC article.
Metastatic colorectal carcinoma-associated fibroblasts have immunosuppressive properties related to increased IGFBP2 expression.
Walterskirchen N, Müller C, Ramos C, Zeindl S, Stang S, Herzog D, Sachet M, Schimek V, Unger L, Gerakopoulos V, Hengstschläger M, Bachleitner-Hofmann T, Bergmann M, Dolznig H, Oehler R. Walterskirchen N, et al. Among authors: dolznig h. Cancer Lett. 2022 Aug 1;540:215737. doi: 10.1016/j.canlet.2022.215737. Epub 2022 May 13. Cancer Lett. 2022. PMID: 35569697 Free article.
Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages.
Stadler M, Pudelko K, Biermeier A, Walterskirchen N, Gaigneaux A, Weindorfer C, Harrer N, Klett H, Hengstschläger M, Schüler J, Sommergruber W, Oehler R, Bergmann M, Letellier E, Dolznig H. Stadler M, et al. Among authors: dolznig h. Cancer Lett. 2021 Nov 1;520:184-200. doi: 10.1016/j.canlet.2021.07.006. Epub 2021 Jul 10. Cancer Lett. 2021. PMID: 34256095 Free article.
Selective Eradication of Colon Cancer Cells Harboring PI3K and/or MAPK Pathway Mutations in 3D Culture by Combined PI3K/AKT/mTOR Pathway and MEK Inhibition.
Atanasova VS, Riedl A, Strobl M, Flandorfer J, Unterleuthner D, Weindorfer C, Neuhold P, Stang S, Hengstschläger M, Bergmann M, Dolznig H. Atanasova VS, et al. Among authors: dolznig h. Int J Mol Sci. 2023 Jan 14;24(2):1668. doi: 10.3390/ijms24021668. Int J Mol Sci. 2023. PMID: 36675180 Free PMC article.
IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer.
Koncina E, Nurmik M, Pozdeev VI, Gilson C, Tsenkova M, Begaj R, Stang S, Gaigneaux A, Weindorfer C, Rodriguez F, Schmoetten M, Klein E, Karta J, Atanasova VS, Grzyb K, Ullmann P, Halder R, Hengstschläger M, Graas J, Augendre V, Karapetyan YE, Kerger L, Zuegel N, Skupin A, Haan S, Meiser J, Dolznig H, Letellier E. Koncina E, et al. Among authors: dolznig h. Nat Commun. 2023 Jul 17;14(1):4251. doi: 10.1038/s41467-023-39953-w. Nat Commun. 2023. PMID: 37460545 Free PMC article.
Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.
Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T. Katholnig K, et al. Among authors: dolznig h. JCI Insight. 2019 Oct 17;4(20):e124164. doi: 10.1172/jci.insight.124164. JCI Insight. 2019. PMID: 31619583 Free PMC article.
KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.
Limberger T, Schlederer M, Trachtová K, Garces de Los Fayos Alonso I, Yang J, Högler S, Sternberg C, Bystry V, Oppelt J, Tichý B, Schmeidl M, Kodajova P, Jäger A, Neubauer HA, Oberhuber M, Schmalzbauer BS, Pospisilova S, Dolznig H, Wadsak W, Culig Z, Turner SD, Egger G, Lagger S, Kenner L. Limberger T, et al. Among authors: dolznig h. Mol Cancer. 2022 Mar 30;21(1):89. doi: 10.1186/s12943-022-01542-8. Mol Cancer. 2022. PMID: 35354467 Free PMC article.
96 results