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652 results

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Page 1
Expanding the Chemical Space of Reverse Fosmidomycin Analogs.
Knak T, Takada S, Illarionov B, Krisilia V, Pessanha de Carvalho L, Lungerich B, Sakamoto Y, Höfmann S, Bacher A, Kalscheuer R, Held J, Fischer M, Tanaka N, Kurz T. Knak T, et al. Among authors: held j. ACS Med Chem Lett. 2024 Dec 23;16(1):136-143. doi: 10.1021/acsmedchemlett.4c00501. eCollection 2025 Jan 9. ACS Med Chem Lett. 2024. PMID: 39811140
TKK130 is a 3-Hydroxy-Propanamidine (HPA) with Potent Antimalarial In Vivo Activity and a High Barrier to Resistance.
Knaab TC, Moritz A, Pessanha de Carvalho L, Klein S, Lungerich B, Lohse K, Kruse L, Mombo-Ngoma G, Orta L, Thibaud JL, de Villiers KA, Fidock DA, Burckhardt BB, Held J, Wittlin S, Kurz T. Knaab TC, et al. Among authors: held j. J Med Chem. 2025 Jan 9;68(1):95-107. doi: 10.1021/acs.jmedchem.4c01465. Epub 2024 Dec 26. J Med Chem. 2025. PMID: 39723908
Targeting the Plasmodium falciparum IspE Enzyme.
Diamanti E, Steinbach AM, de Carvalho LP, Ropponen HK, Lacour A, Hamid R, Eisa S, Bravo P, Bousis S, Illarionov B, Fischer M, Hamed MM, Bach NC, Rottmann M, Held J, Witschel M, Sieber SA, Hirsch AKH. Diamanti E, et al. Among authors: held j. ACS Omega. 2024 Oct 25;9(44):44465-44473. doi: 10.1021/acsomega.4c06038. eCollection 2024 Nov 5. ACS Omega. 2024. PMID: 39524657 Free PMC article.
A comparison of isolated limb infusion/perfusion, immune checkpoint inhibitors, and intralesional therapy as first-line treatment for patients with melanoma in-transit metastases.
DePalo DK, Dugan MM, Naqvi SMH, Ollila DW, Hieken TJ, Block MS, van Houdt WJ, Wouters MWJM, Reijers SJM, Asher N, Broman KK, Duncan Z, Anderson M, Gyorki DE, Snow H, Held J, Farma JM, Vetto JT, Hui JYC, Kolbow M, Saw RPM, Lo SN, Long GV, Thompson JF, Kim Y, Karapetyan L, Ny L, van Akkooi ACJ, Olofsson Bagge R, Zager JS. DePalo DK, et al. Among authors: held j. Cancer. 2025 Jan 1;131(1):e35636. doi: 10.1002/cncr.35636. Epub 2024 Nov 10. Cancer. 2025. PMID: 39522025
[Small renal mass: which criteria are decisive for a tumor board?].
Dräger DL, Rojas Cruz C, Held J, Niepel F, Zimpfer A, Hakenberg OW. Dräger DL, et al. Among authors: held j. Urologie. 2024 Dec;63(12):1217-1223. doi: 10.1007/s00120-024-02471-8. Epub 2024 Nov 6. Urologie. 2024. PMID: 39505775 Review. German.
652 results