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854 results

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Page 1
Deep generative design of RNA aptamers using structural predictions.
Wong F, He D, Krishnan A, Hong L, Wang AZ, Wang J, Hu Z, Omori S, Li A, Rao J, Yu Q, Jin W, Zhang T, Ilia K, Chen JX, Zheng S, King I, Li Y, Collins JJ. Wong F, et al. Among authors: collins jj. Nat Comput Sci. 2024 Nov;4(11):829-839. doi: 10.1038/s43588-024-00720-6. Epub 2024 Nov 6. Nat Comput Sci. 2024. PMID: 39506080
A Deep Learning Approach to Antibiotic Discovery.
Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. Stokes JM, et al. Among authors: collins jj. Cell. 2020 Feb 20;180(4):688-702.e13. doi: 10.1016/j.cell.2020.01.021. Cell. 2020. PMID: 32084340 Free PMC article.
A deep learning approach to programmable RNA switches.
Angenent-Mari NM, Garruss AS, Soenksen LR, Church G, Collins JJ. Angenent-Mari NM, et al. Among authors: collins jj. Nat Commun. 2020 Oct 7;11(1):5057. doi: 10.1038/s41467-020-18677-1. Nat Commun. 2020. PMID: 33028812 Free PMC article.
Evidence that coronavirus superspreading is fat-tailed.
Wong F, Collins JJ. Wong F, et al. Among authors: collins jj. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29416-29418. doi: 10.1073/pnas.2018490117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139561 Free PMC article.
Deep learning identifies synergistic drug combinations for treating COVID-19.
Jin W, Stokes JM, Eastman RT, Itkin Z, Zakharov AV, Collins JJ, Jaakkola TS, Barzilay R. Jin W, et al. Among authors: collins jj. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2105070118. doi: 10.1073/pnas.2105070118. Proc Natl Acad Sci U S A. 2021. PMID: 34526388 Free PMC article.
Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality.
Lobritz MA, Andrews IW, Braff D, Porter CBM, Gutierrez A, Furuta Y, Cortes LBG, Ferrante T, Bening SC, Wong F, Gruber C, Bakerlee CW, Lambert G, Walker GC, Dwyer DJ, Collins JJ. Lobritz MA, et al. Among authors: collins jj. Cell Chem Biol. 2022 Feb 17;29(2):276-286.e4. doi: 10.1016/j.chembiol.2021.12.010. Epub 2022 Jan 5. Cell Chem Biol. 2022. PMID: 34990601 Free PMC article.
Synthetic genetic circuits to uncover and enforce the OCT4 trajectories of successful reprogramming of human fibroblasts.
Ilia K, Shakiba N, Bingham T, Jones RD, Kaminski MM, Aravera E, Bruno S, Palacios S, Weiss R, Collins JJ, Del Vecchio D, Schlaeger TM. Ilia K, et al. Among authors: collins jj. bioRxiv [Preprint]. 2023 Jan 25:2023.01.25.525529. doi: 10.1101/2023.01.25.525529. bioRxiv. 2023. Update in: Sci Adv. 2023 Dec;9(48):eadg8495. doi: 10.1126/sciadv.adg8495 PMID: 36747813 Free PMC article. Updated. Preprint.
854 results