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The First Pilot Epigenetic Type Improvement of Neuropsychiatric Symptoms in a Polymorphic Dopamine D2 (-DRD2/ANKK (Taq1A)), OPRM1 (A/G), DRD3 (C/T), and MAOA (4R) Compromised Preadolescence Male with Putative PANDAS/CANS: Positive Clinical Outcome with Precision-Guided DNA Testing and Pro-Dopamine Regulation (KB220) and Antibacterial Therapies.
Blum K, Elman I, Han D, Hanna C, Baron D, Gupta A, Kazmi S, Khalsa J, Bagchi D, McLaughlin T, Badgaiyan RD, Modestino EJ, Edwards D, Dennen CA, Braverman ER, Bowirrat A, Sunder K, Murphy K, Jafari N, Zeine F, Carney PR, Gold MS, Lewandowski KU, Sharafshah A, Pollack AR, Thanos PK. Blum K, et al. Among authors: bagchi d. Open J Immunol. 2024 Sep;14(3):60-86. doi: 10.4236/oji.2024.143006. Open J Immunol. 2024. PMID: 39507617 Free PMC article.
Should Reward Deficiency Syndrome (RDS) Be Considered an Umbrella Disorder for Mental Illness and Associated Genetic and Epigenetic Induced Dysregulation of Brain Reward Circuitry?
Blum K, Dennen CA, Elman I, Bowirrat A, Thanos PK, Badgaiyan RD, Downs BW, Bagchi D, Baron D, Braverman ER, Gupta A, Green R, McLaughlin T, Barh D, Gold MS. Blum K, et al. Among authors: bagchi d. J Pers Med. 2022 Oct 14;12(10):1719. doi: 10.3390/jpm12101719. J Pers Med. 2022. PMID: 36294858 Free PMC article.
Hypothesizing That Pediatric Autoimmune Neuropsychiatric Associated Streptococcal (PANDAS) Causes Rapid Onset of Reward Deficiency Syndrome (RDS) Behaviors and May Require Induction of "Dopamine Homeostasis".
Blum K, Dennen CA, Braverman ER, Gupta A, Baron D, Downs BW, Bagchi D, Thanos P, Pollock M, Khalsa J, Elman I, Bowirrat A, Badgaiyan RA. Blum K, et al. Among authors: bagchi d. Open J Immunol. 2022 Sep;12(3):65-75. doi: 10.4236/oji.2022.123004. Open J Immunol. 2022. PMID: 36407790 Free PMC article.
Futuristic Thinking about Engineering "Geneospirituality" to Help Prevent Relapse of Reward Deficiency Syndrome (RDS) Behaviors.
Blum K, McLaughlin T, Bowirrat A, Bagchi D, Braverman ER, Gupta A, Baron D, Thanos PK, Khalsa J, Jafari N, Zeine F, Giordano J, Dennen CA, Madigan MA, Carney P, Gold MS, Sunder K, Badgaiyan RD. Blum K, et al. Among authors: bagchi d. EC Psychol Psychiatr. 2023 Feb 16;12(3):26-32. EC Psychol Psychiatr. 2023. PMID: 37361347 Free PMC article.
Invited Expert Opinion- Bioinformatic and Limitation Directives to Help Adopt Genetic Addiction Risk Screening and Identify Preaddictive Reward Dysregulation: Required Analytic Evidence to Induce Dopamine Homeostatsis.
Blum K, Gold MS, Cadet JL, Gondre-Lewis MC, McLaughlin T, Braverman ER, Elman I, Paul Carney B, Cortese R, Abijo T, Bagchi D, Giordano J, Dennen CA, Baron D, Thanos PK, Soni D, Makale MT, Makale M, Murphy KT, Jafari N, Sunder K, Zeine F, Ceccanti M, Bowirrat A, Badgaiyan RD. Blum K, et al. Among authors: bagchi d. Med Res Arch. 2023 Sep 14;11(8):10.18103/mra.v11i8.4211. doi: 10.18103/mra.v11i8.4211. Med Res Arch. 2023. PMID: 37885438 Free PMC article. No abstract available.
Identification of stress-induced epigenetic methylation onto dopamine D2 gene and neurological and behavioral consequences.
Blum K, Bowirrat A, Baron D, Elman I, Makale MT, Cadet JL, Thanos PK, Hanna C, Ahmed R, Gondre-Lewis MC, Dennen CA, Braverman ER, Soni D, Carney P, Khalsa J, Modestino EJ, Barh D, Bagchi D, Badgaiyan RD, McLaughlin T, Cortese R, Ceccanti M, Murphy KT, Gupta A, Makale MT, Sunder K, Gold MS. Blum K, et al. Among authors: bagchi d. Gene Protein Dis. 2024 Mar 29;3(1):10.36922/gpd.1966. doi: 10.36922/gpd.1966. Gene Protein Dis. 2024. PMID: 38766604 Free PMC article.
A historical perspective on clonidine as an alpha-2A receptor agonist in the treatment of addictive behaviors: Focus on opioid dependence.
Gold MS, Blum K, Bowirrat A, Pinhasov A, Bagchi D, Dennen CA, Thanos PK, Hanna C, Lewandrowski KU, Sharafshah A, Elman I, Badgaiyan RD. Gold MS, et al. Among authors: bagchi d. INNOSC Theranostics Pharmacol Sci. 2024;7(3):1918. doi: 10.36922/itps.1918. Epub 2024 Jul 29. INNOSC Theranostics Pharmacol Sci. 2024. PMID: 39119149 Free PMC article.
Is There a Natural, Non-addictive, and Non-anti-reward, Safe, Gene-based Solution to Treat Reward Deficiency Syndrome? KB220 Variants vs GLP-1 Analogs.
Modestino EJ, Bowirrat A, Baron D, Thanos PK, Hanna C, Bagchi D, Braverman ER, Dennen CA, Badgaiyan RD, Pollack AR, Lewandrowski KU, Sharafshah A, Gold MS, Blum K. Modestino EJ, et al. Among authors: bagchi d. J Addict Psychiatry. 2024;8(1):34-49. Epub 2024 May 20. J Addict Psychiatry. 2024. PMID: 39618491 Free PMC article.
Solving the Global Opioid Crisis: Incorporating Genetic Addiction Risk Assessment with Personalized Dopaminergic Homeostatic Therapy and Awareness Integration Therapy.
Zeine F, Jafari N, Baron D, Bowirrat A, Pinhasov A, Norling B, Martinez KC, Nami M, Manavi N, Sunder K, Rabin DM, Bagchi D, Khalsa J, Gold MS, Sipple D, Barzegar M, Bodhanapati J, Khader W, Carney P, Dennen CA, Gupta A, Elman I, Badgaiyan RD, Modestino EJ, Thanos PK, Hanna C, McLaughlin T, Cadet JL, Soni D, Braverman ER, Barh D, Giordano J, Edwards D, Ashford JW, Gondre-Lewis MC, Gilley E, Murphy KT, Lewandrowski KU, Sharafshah A, Makale M, Fuehrlein B, Blum K. Zeine F, et al. Among authors: bagchi d. J Addict Psychiatry. 2024;8(1):50-95. Epub 2024 Jun 20. J Addict Psychiatry. 2024. PMID: 39635461 Free PMC article.
432 results