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Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction-Orbitrap mass spectrometry.
Oates RN, Lieu LB, Kline JT, Mullen C, Srzentić K, Huguet R, McAlister GC, Huang J, Bergen D, Melani RD, Zabrouskov V, Durbin KR, Syka JEP, Fornelli L. Oates RN, et al. Among authors: syka jep. Anal Bioanal Chem. 2024 Nov;416(28):6463-6472. doi: 10.1007/s00216-024-05534-z. Epub 2024 Sep 16. Anal Bioanal Chem. 2024. PMID: 39283368
Infrared Multiphoton Dissociation Enables Top-Down Characterization of Membrane Protein Complexes and G Protein-Coupled Receptors.
Lutomski CA, El-Baba TJ, Hinkle JD, Liko I, Bennett JL, Kalmankar NV, Dolan A, Kirschbaum C, Greis K, Urner LH, Kapoor P, Yen HY, Pagel K, Mullen C, Syka JEP, Robinson CV. Lutomski CA, et al. Among authors: syka jep. Angew Chem Int Ed Engl. 2023 Sep 4;62(36):e202305694. doi: 10.1002/anie.202305694. Epub 2023 Jul 25. Angew Chem Int Ed Engl. 2023. PMID: 37329506 Free PMC article.
Infrared Multiphoton Dissociation Enables Top-Down Characterization of Membrane Protein Complexes and G Protein-Coupled Receptors.
Lutomski CA, El-Baba TJ, Hinkle JD, Liko I, Bennett JL, Kalmankar NV, Dolan A, Kirschbaum C, Greis K, Urner LH, Kapoor P, Yen HY, Pagel K, Mullen C, Syka JEP, Robinson CV. Lutomski CA, et al. Among authors: syka jep. Angew Chem Weinheim Bergstr Ger. 2023 Sep 4;135(36):e202305694. doi: 10.1002/ange.202305694. Epub 2023 Jul 25. Angew Chem Weinheim Bergstr Ger. 2023. PMID: 38516403 Free PMC article.
Exposing the molecular heterogeneity of glycosylated biotherapeutics.
Schachner LF, Mullen C, Phung W, Hinkle JD, Beardsley MI, Bentley T, Day P, Tsai C, Sukumaran S, Baginski T, DiCara D, Agard NJ, Masureel M, Gober J, ElSohly AM, Melani R, Syka JEP, Huguet R, Marty MT, Sandoval W. Schachner LF, et al. Among authors: syka jep. Nat Commun. 2024 Apr 16;15(1):3259. doi: 10.1038/s41467-024-47693-8. Nat Commun. 2024. PMID: 38627419 Free PMC article.
36 results