Garone MG - Search Results

1

HuD impairs neuromuscular junctions and induces apoptosis in human iPSC and Drosophila ALS models.

Silvestri B, Mochi M, Mawrie D, de Turris V, Colantoni A, Borhy B, Medici M, Anderson EN, Garone MG, Zammerilla CP, Simula M, Ballarino M, Pandey UB, Rosa A. Silvestri B, et al. Among authors: garone mg. Nat Commun. 2024 Nov 7;15(1):9618. doi: 10.1038/s41467-024-54004-8. Nat Commun. 2024. PMID: 39511225 Free PMC article.

2

Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.

De Santis R, Alfano V, de Turris V, Colantoni A, Santini L, Garone MG, Antonacci G, Peruzzi G, Sudria-Lopez E, Wyler E, Anink JJ, Aronica E, Landthaler M, Pasterkamp RJ, Bozzoni I, Rosa A. De Santis R, et al. Among authors: garone mg. Cell Rep. 2019 Jun 25;27(13):3818-3831.e5. doi: 10.1016/j.celrep.2019.05.085. Cell Rep. 2019. PMID: 31242416 Free PMC article.

3

ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity.

Garone MG, Birsa N, Rosito M, Salaris F, Mochi M, de Turris V, Nair RR, Cunningham TJ, Fisher EMC, Morlando M, Fratta P, Rosa A. Garone MG, et al. Commun Biol. 2021 Sep 1;4(1):1025. doi: 10.1038/s42003-021-02538-8. Commun Biol. 2021. PMID: 34471224 Free PMC article.

4

Emerging Roles for the RNA-Binding Protein HuD (ELAVL4) in Nervous System Diseases.

Silvestri B, Mochi M, Garone MG, Rosa A. Silvestri B, et al. Among authors: garone mg. Int J Mol Sci. 2022 Nov 23;23(23):14606. doi: 10.3390/ijms232314606. Int J Mol Sci. 2022. PMID: 36498933 Free PMC article. Review.

5

HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in in vitro and in vivo models of amyotrophic lateral sclerosis.

Silvestri B, Mochi M, Mawrie D, de Turris V, Colantoni A, Borhy B, Medici M, Anderson EN, Garone MG, Zammerilla CP, Pandey UB, Rosa A. Silvestri B, et al. Among authors: garone mg. bioRxiv [Preprint]. 2024 Mar 1:2023.08.22.554258. doi: 10.1101/2023.08.22.554258. bioRxiv. 2024. PMID: 38464028 Free PMC article. Preprint.

6

Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector.

De Santis R, Garone MG, Pagani F, de Turris V, Di Angelantonio S, Rosa A. De Santis R, et al. Among authors: garone mg. Stem Cell Res. 2018 May;29:189-196. doi: 10.1016/j.scr.2018.04.012. Epub 2018 Apr 27. Stem Cell Res. 2018. PMID: 29729503 Free article.

7

Conversion of Human Induced Pluripotent Stem Cells (iPSCs) into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors.

Garone MG, de Turris V, Soloperto A, Brighi C, De Santis R, Pagani F, Di Angelantonio S, Rosa A. Garone MG, et al. J Vis Exp. 2019 May 1;(147). doi: 10.3791/59321. J Vis Exp. 2019. PMID: 31107442

8

Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3'UTR binding.

Garone MG, Alfano V, Salvatori B, Braccia C, Peruzzi G, Colantoni A, Bozzoni I, Armirotti A, Rosa A. Garone MG, et al. Sci Rep. 2020 Jul 16;10(1):11827. doi: 10.1038/s41598-020-68794-6. Sci Rep. 2020. PMID: 32678235 Free PMC article.

9

Culture of Human iPSC-Derived Motoneurons in Compartmentalized Microfluidic Devices and Quantitative Assays for Studying Axonal Phenotypes.

Garone MG, D'Antoni C, Rosa A. Garone MG, et al. Methods Mol Biol. 2022;2429:189-199. doi: 10.1007/978-1-0716-1979-7_12. Methods Mol Biol. 2022. PMID: 35507162

10

Digital color-coded molecular barcoding reveals dysregulation of common FUS and FMRP targets in soma and neurites of ALS mutant motoneurons.

Garone MG, Salerno D, Rosa A. Garone MG, et al. Cell Death Discov. 2023 Jan 26;9(1):33. doi: 10.1038/s41420-023-01340-1. Cell Death Discov. 2023. PMID: 36702823 Free PMC article.

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