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The polymeric fluoropyrimidine CF10 overcomes limitations of 5-FU in pancreatic ductal adenocarcinoma cells through increased replication stress.
Finan JM, Di Niro R, Park SY, Jeong KJ, Hedberg MD, Smith A, McCarthy GA, Haber AO, Muschler J, Sears RC, Mills GB, Gmeiner WH, Brody JR. Finan JM, et al. Among authors: mccarthy ga. Cancer Biol Ther. 2024 Dec 31;25(1):2421584. doi: 10.1080/15384047.2024.2421584. Epub 2024 Nov 8. Cancer Biol Ther. 2024. PMID: 39513592 Free PMC article.
The RNA-Binding Protein HuR Posttranscriptionally Regulates the Protumorigenic Activator YAP1 in Pancreatic Ductal Adenocarcinoma.
Brown SZ, McCarthy GA, Carroll JR, Di Niro R, Pelz C, Jain A, Sutton TL, Holly HD, Nevler A, Schultz CW, McCoy MD, Cozzitorto JA Jr, Jiang W, Yeo CJ, Dixon DA, Sears RC, Brody JR. Brown SZ, et al. Among authors: mccarthy ga. Mol Cell Biol. 2022 Jul 21;42(7):e0001822. doi: 10.1128/mcb.00018-22. Epub 2022 Jun 15. Mol Cell Biol. 2022. PMID: 35703534 Free PMC article.
Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer.
Jain A, Agostini LC, McCarthy GA, Chand SN, Ramirez A, Nevler A, Cozzitorto J, Schultz CW, Lowder CY, Smith KM, Waddell ID, Raitses-Gurevich M, Stossel C, Gorman YG, Atias D, Yeo CJ, Winter JM, Olive KP, Golan T, Pishvaian MJ, Ogilvie D, James DI, Jordan AM, Brody JR. Jain A, et al. Among authors: mccarthy ga. Cancer Res. 2019 Sep 1;79(17):4491-4502. doi: 10.1158/0008-5472.CAN-18-3645. Epub 2019 Jul 4. Cancer Res. 2019. PMID: 31273064 Free PMC article.
The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria.
Schultz CW, McCarthy GA, Nerwal T, Nevler A, DuHadaway JB, McCoy MD, Jiang W, Brown SZ, Goetz A, Jain A, Calvert VS, Vishwakarma V, Wang D, Preet R, Cassel J, Summer R, Shaghaghi H, Pommier Y, Baechler SA, Pishvaian MJ, Golan T, Yeo CJ, Petricoin EF, Prendergast GC, Salvino J, Singh PK, Dixon DA, Brody JR. Schultz CW, et al. Among authors: mccarthy ga. Mol Cancer Ther. 2021 Nov;20(11):2166-2176. doi: 10.1158/1535-7163.MCT-20-0652. Epub 2021 Aug 19. Mol Cancer Ther. 2021. PMID: 34413127 Free PMC article.
A Novel 3DNA® Nanocarrier effectively delivers payloads to pancreatic tumors.
McCarthy GA, Jain A, Di Niro R, Schultz CW, Jiang W, Yeo CJ, Bowers J, Finan J, Rhodes K, Casta L, Hou V, Stefanoni A, Brown SZ, Nevler A, Agostini LC, Getts L, Getts R, Brody JR. McCarthy GA, et al. Transl Oncol. 2023 Jun;32:101662. doi: 10.1016/j.tranon.2023.101662. Epub 2023 Mar 31. Transl Oncol. 2023. PMID: 37004490 Free PMC article.
14 results