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17 results

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Page 1
PU.1 eviction at lymphocyte-specific chromatin domains mediates glucocorticoid response in acute lymphoblastic leukemia.
Beck D, Cao H, Tian F, Huang Y, Jiang M, Zhao H, Tai X, Xu W, Kosasih HJ, Kealy DJ, Zhao W, Taylor SJ, Couttas TA, Song G, Chacon-Fajardo D, Walia Y, Wang M, Dowle AA, Holding AN, Bridge KS, Zhang C, Wang J, Mi JQ, Lock RB, de Bock CE, Jing D. Beck D, et al. Among authors: kosasih hj. Nat Commun. 2024 Nov 8;15(1):9697. doi: 10.1038/s41467-024-54096-2. Nat Commun. 2024. PMID: 39516193 Free PMC article.
The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia.
Toscan CE, McCalmont H, Ashoorzadeh A, Lin X, Fu Z, Doculara L, Kosasih HJ, Cadiz R, Zhou A, Williams S, Evans K, Khalili F, Cai R, Yeats KL, Gifford AJ, Pickford R, Mayoh C, Xie J, Henderson MJ, Trahair TN, Patterson AV, Smaill JB, de Bock CE, Lock RB. Toscan CE, et al. Among authors: kosasih hj. Blood Cancer J. 2024 Nov 6;14(1):192. doi: 10.1038/s41408-024-01180-x. Blood Cancer J. 2024. PMID: 39505850 Free PMC article.
Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma.
De Coninck S, De Smedt R, Lintermans B, Reunes L, Kosasih HJ, Reekmans A, Brown LM, Van Roy N, Palhais B, Roels J, Van der Linden M, Van Dorpe J, Ntziachristos P, Van Delft FW, Mansour MR, Pieters T, Lammens T, De Moerloose B, De Bock CE, Goossens S, Van Vlierberghe P. De Coninck S, et al. Among authors: kosasih hj. Haematologica. 2024 May 1;109(5):1373-1384. doi: 10.3324/haematol.2023.283981. Haematologica. 2024. PMID: 37941480 Free PMC article.
Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL.
Sadras T, Jalud FB, Kosasih HJ, Horne CR, Brown LM, El-Kamand S, de Bock CE, McAloney L, Ng AP, Davidson NM, Ludlow LEA, Oshlack A, Cowley MJ, Khaw SL, Murphy JM, Ekert PG. Sadras T, et al. Among authors: kosasih hj. Leukemia. 2023 Apr;37(4):905-909. doi: 10.1038/s41375-023-01843-x. Epub 2023 Feb 21. Leukemia. 2023. PMID: 36810896 Free PMC article. No abstract available.
SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia.
Brown LM, Hediyeh-Zadeh S, Sadras T, Huckstep H, Sandow JJ, Bartolo RC, Kosasih HJ, Davidson NM, Schmidt B, Bjelosevic S, Johnstone R, Webb AI, Khaw SL, Oshlack A, Davis MJ, Ekert PG. Brown LM, et al. Among authors: kosasih hj. Blood Adv. 2022 Apr 12;6(7):2373-2387. doi: 10.1182/bloodadvances.2021006076. Blood Adv. 2022. PMID: 35061886 Free PMC article.
A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax.
Kosasih HJ, Healey G, Brennan MS, Bjelosevic S, Sadras T, Jalud FB, Ibnat T, Ng AP, Mayoh C, Mao J, Tax G, Ludlow LEA, Johnstone RW, Herold MJ, Khaw SL, de Bock CE, Ekert PG. Kosasih HJ, et al. Hemasphere. 2024 Feb 14;8(2):e1. doi: 10.1002/hem3.1. eCollection 2024 Feb. Hemasphere. 2024. PMID: 38435422 Free PMC article. No abstract available.
ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia.
Schmidt B, Brown LM, Ryland GL, Lonsdale A, Kosasih HJ, Ludlow LE, Majewski IJ, Blombery P, Ekert PG, Davidson NM, Oshlack A. Schmidt B, et al. Among authors: kosasih hj. Blood Adv. 2022 Jul 26;6(14):4093-4097. doi: 10.1182/bloodadvances.2021005894. Blood Adv. 2022. PMID: 35482550 Free PMC article. No abstract available.
17 results