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The protease activated receptor 2 - CCAAT/enhancer-binding protein beta - SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis.
Villano G, Novo E, Turato C, Quarta S, Ruvoletto M, Biasiolo A, Protopapa F, Chinellato M, Martini A, Trevellin E, Granzotto M, Cannito S, Cendron L, De Siervi S, Guido M, Parola M, Vettor R, Pontisso P. Villano G, et al. Mol Metab. 2024 Mar;81:101889. doi: 10.1016/j.molmet.2024.101889. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307387 Free PMC article.
SerpinB3 Upregulates Low-Density Lipoprotein Receptor-Related Protein (LRP) Family Members, Leading to Wnt Signaling Activation and Increased Cell Survival and Invasiveness.
Quarta S, Cappon A, Turato C, Ruvoletto M, Cannito S, Villano G, Biasiolo A, Maggi M, Protopapa F, Bertazza L, Fasolato S, Parola M, Pontisso P. Quarta S, et al. Among authors: villano g. Biology (Basel). 2023 May 26;12(6):771. doi: 10.3390/biology12060771. Biology (Basel). 2023. PMID: 37372056 Free PMC article.
SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease.
Novo E, Cappon A, Villano G, Quarta S, Cannito S, Bocca C, Turato C, Guido M, Maggiora M, Protopapa F, Sutti S, Provera A, Ruvoletto M, Biasiolo A, Foglia B, Albano E, Pontisso P, Parola M. Novo E, et al. Among authors: villano g. Front Immunol. 2022 Jul 8;13:910526. doi: 10.3389/fimmu.2022.910526. eCollection 2022. Front Immunol. 2022. PMID: 35874657 Free PMC article.
SERPINB3 is associated with longer survival in transgenic mice.
Villano G, Ruvoletto M, Ceolotto G, Quarta S, Calabrese F, Turato C, Tono N, Crescenzi M, Biasiolo A, Cattelan A, Merkel C, Avogaro A, Gatta A, Pontisso P. Villano G, et al. Sci Rep. 2013 Oct 28;3:3056. doi: 10.1038/srep03056. Sci Rep. 2013. PMID: 24162160 Free PMC article.
33 results