He Z - Search Results

1

Taohe Chengqi decoction improves diabetic cognitive dysfunction by alleviating neural stem cell senescence through HIF1α-driven metabolic signaling.

Qin T, He Z, Hassan HM, Wang Q, Shi L, Yu Y, Zhou Y, Zhang W, Yuan Z. Qin T, et al. Among authors: he z. Phytomedicine. 2024 Dec;135:156219. doi: 10.1016/j.phymed.2024.156219. Epub 2024 Nov 5. Phytomedicine. 2024. PMID: 39520950

2

Formononetin Mitigates Liver Fibrosis via Promoting Hepatic Stellate Cell Senescence and Inhibiting EZH2/YAP Axis.

Yuan Z, Meng J, Shen X, Wang M, Yu Y, Shi L, Li YL, Hassan HM, Li H, He ZX, Qin T. Yuan Z, et al. Among authors: he zx. J Agric Food Chem. 2024 Oct 3. doi: 10.1021/acs.jafc.4c05529. Online ahead of print. J Agric Food Chem. 2024. PMID: 39360779

3

A comprehensive review on DCN1 protein, inhibitors and their therapeutic applications.

He Z, Yuan Z, Yang F, Zhang J, Zhao W, Qin T, Zheng X, Ma L. He Z, et al. Int J Biol Macromol. 2024 Oct;277(Pt 4):134541. doi: 10.1016/j.ijbiomac.2024.134541. Epub 2024 Aug 5. Int J Biol Macromol. 2024. PMID: 39111501 Review.

4

Recent advances of Pin1 inhibitors as potential anticancer agents.

Bai Y, Yuan Z, Yuan S, He Z. Bai Y, et al. Among authors: he z. Bioorg Chem. 2024 Mar;144:107171. doi: 10.1016/j.bioorg.2024.107171. Epub 2024 Feb 3. Bioorg Chem. 2024. PMID: 38325131 Review.

5

Targeting histone deacetylases for heart diseases.

Jin G, Wang K, Zhao Y, Yuan S, He Z, Zhang J. Jin G, et al. Among authors: he z. Bioorg Chem. 2023 Sep;138:106601. doi: 10.1016/j.bioorg.2023.106601. Epub 2023 May 10. Bioorg Chem. 2023. PMID: 37224740 Review.

6

Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.

Zhou W, Dong G, Gao G, He Z, Xu J, Aziz S, Ma L, Zhao W. Zhou W, et al. Among authors: he z. Biochem Cell Biol. 2022 Aug 1;100(4):309-324. doi: 10.1139/bcb-2021-0585. Epub 2022 May 11. Biochem Cell Biol. 2022. PMID: 35544948

7

Discovery of a novel 1H-pyrazole- [3,4-b] pyridine-based lysine demethylase 5B inhibitor with potential anti-prostate cancer activity that perturbs the phosphoinositide 3-kinase/AKT pathway.

Cao Y, Yang P, Yang Y, Lin Z, Fan Z, Wei X, Yan L, Li Y, He Z, Ma L, Xu H, Wu C. Cao Y, et al. Among authors: he z. Eur J Med Chem. 2023 May 5;251:115250. doi: 10.1016/j.ejmech.2023.115250. Epub 2023 Mar 11. Eur J Med Chem. 2023. PMID: 36931124

8

Discovery of Novel Imidazo[1,2-a]pyridine-Based HDAC6 Inhibitors as an Anticarcinogen with a Cardioprotective Effect.

Yang FF, Liu JJ, Xu XL, Hu T, Liu JQ, He ZX, Zhao GY, Wei B, Ma LY. Yang FF, et al. J Med Chem. 2024 Aug 22;67(16):14345-14369. doi: 10.1021/acs.jmedchem.4c01168. Epub 2024 Aug 5. J Med Chem. 2024. PMID: 39102466

9

A comprehensive review of small molecule drugs approved by the FDA in 2023: Advances and prospects.

Bai YR, Seng DJ, Xu Y, Zhang YD, Zhou WJ, Jia YY, Song J, He ZX, Liu HM, Yuan S. Bai YR, et al. Eur J Med Chem. 2024 Oct 5;276:116706. doi: 10.1016/j.ejmech.2024.116706. Epub 2024 Jul 22. Eur J Med Chem. 2024. PMID: 39053188 Review.

10

Discovery of 1,2,4-Triazole-3-thione Derivatives as Potent and Selective DCN1 Inhibitors for Pathological Cardiac Fibrosis and Remodeling.

He ZX, Gao G, Qiao H, Dong GJ, Dan Z, Li YL, Qi YR, Zhang Q, Yuan S, Liu HM, Dong J, Zhao W, Ma LY. He ZX, et al. J Med Chem. 2024 Nov 14;67(21):18699-18723. doi: 10.1021/acs.jmedchem.4c00713. Epub 2024 Aug 19. J Med Chem. 2024. PMID: 39158077

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