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Page 1
Preclinical validation of human recombinant glutamate-oxaloacetate transaminase for the treatment of acute ischemic stroke.
Pérez-Mato M, Dopico-López A, Akkoc Y, López-Amoedo S, Correa-Paz C, Candamo-Lourido M, Iglesias-Rey R, López-Arias E, Bugallo-Casal A, da Silva-Candal A, Bravo SB, Chantada-Vázquez MDP, Arias S, Santamaría-Cadavid M, Estany-Gestal A, Zaghmi A, Gauthier MA, Gutiérrez-Fernández M, Martin A, Llop J, Rodríguez C, Almeida Á, Migliavacca M, Polo E, Pelaz B, Gozuacik D, El Yamani N, SenGupta T, Rundén-Pran E, Vivancos J, Castellanos M, Díez-Tejedor E, Sobrino T, Rabinkov A, Mirelman D, Castillo J, Campos F. Pérez-Mato M, et al. Among authors: gutierrez fernandez m. iScience. 2024 Oct 9;27(11):111108. doi: 10.1016/j.isci.2024.111108. eCollection 2024 Nov 15. iScience. 2024. PMID: 39524351 Free PMC article.
Blood glutamate grabbing does not reduce the hematoma in an intracerebral hemorrhage model but it is a safe excitotoxic treatment modality.
da Silva-Candal A, Vieites-Prado A, Gutiérrez-Fernández M, Rey RI, Argibay B, Mirelman D, Sobrino T, Rodríguez-Frutos B, Castillo J, Campos F. da Silva-Candal A, et al. J Cereb Blood Flow Metab. 2015 Jul;35(7):1206-12. doi: 10.1038/jcbfm.2015.28. Epub 2015 Mar 4. J Cereb Blood Flow Metab. 2015. PMID: 25735920 Free PMC article.
Sustained blood glutamate scavenging enhances protection in ischemic stroke.
Zaghmi A, Dopico-López A, Pérez-Mato M, Iglesias-Rey R, Hervella P, Greschner AA, Bugallo-Casal A, da Silva A, Gutiérrez-Fernández M, Castillo J, Pérez FC, Gauthier MA. Zaghmi A, et al. Commun Biol. 2020 Dec 3;3(1):729. doi: 10.1038/s42003-020-01406-1. Commun Biol. 2020. PMID: 33273696 Free PMC article.
Recovery After Stroke: New Insight to Promote Brain Plasticity.
Otero-Ortega L, Gutiérrez-Fernández M, Díez-Tejedor E. Otero-Ortega L, et al. Front Neurol. 2021 Nov 19;12:768958. doi: 10.3389/fneur.2021.768958. eCollection 2021. Front Neurol. 2021. PMID: 34867756 Free PMC article. No abstract available.
Circulating Extracellular Vesicle Proteins and MicroRNA Profiles in Subcortical and Cortical-Subcortical Ischaemic Stroke.
Otero-Ortega L, Alonso-López E, Pérez-Mato M, Laso-García F, Gómez-de Frutos MC, Diekhorst L, García-Bermejo ML, Conde-Moreno E, Fuentes B, de Leciñana MA, Bravo SB, Díez-Tejedor E, Gutiérrez-Fernández M. Otero-Ortega L, et al. Biomedicines. 2021 Jul 7;9(7):786. doi: 10.3390/biomedicines9070786. Biomedicines. 2021. PMID: 34356850 Free PMC article.
Protein content of blood-derived extracellular vesicles: An approach to the pathophysiology of cerebral hemorrhage.
Laso-García F, Piniella D, Gómez-de Frutos MC, Casado-Fernández L, Pérez-Mato M, Alonso-López E, Otero-Ortega L, Bravo SB, Chantada-Vázquez MDP, Trilla-Fuertes L, Fresno-Vara JÁ, Fuentes B, Díez-Tejedor E, Gutiérrez-Fernández M, Alonso De Leciñana M. Laso-García F, et al. Front Cell Neurosci. 2023 Jan 19;16:1058546. doi: 10.3389/fncel.2022.1058546. eCollection 2022. Front Cell Neurosci. 2023. PMID: 36776230 Free PMC article.
Circulating extracellular vesicles promote recovery in a preclinical model of intracerebral hemorrhage.
Laso-García F, Casado-Fernández L, Piniella D, Gómez-de Frutos MC, Arizaga-Echebarria JK, Pérez-Mato M, Alonso-López E, Otero-Ortega L, Bravo SB, Chantada-Vázquez MDP, Avendaño-Ortiz J, López-Collazo E, Lumbreras-Herrera MI, Gámez-Pozo A, Fuentes B, Díez-Tejedor E, Gutiérrez-Fernández M, Alonso de Leciñana M. Laso-García F, et al. Among authors: gutierrez fernandez m. Mol Ther Nucleic Acids. 2023 Mar 21;32:247-262. doi: 10.1016/j.omtn.2023.03.006. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37090418 Free PMC article.
Reparative therapy for acute ischemic stroke with allogeneic mesenchymal stem cells from adipose tissue: a safety assessment: a phase II randomized, double-blind, placebo-controlled, single-center, pilot clinical trial.
Díez-Tejedor E, Gutiérrez-Fernández M, Martínez-Sánchez P, Rodríguez-Frutos B, Ruiz-Ares G, Lara ML, Gimeno BF. Díez-Tejedor E, et al. J Stroke Cerebrovasc Dis. 2014 Nov-Dec;23(10):2694-2700. doi: 10.1016/j.jstrokecerebrovasdis.2014.06.011. Epub 2014 Oct 7. J Stroke Cerebrovasc Dis. 2014. PMID: 25304723 Clinical Trial.
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