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ASC specks as a single-molecule fluid biomarker of inflammation in neurodegenerative diseases.
Lobanova E, Zhang YP, Emin D, Brelstaff J, Kahanawita L, Malpetti M, Quaegebeur A, Triantafilou K, Triantafilou M, Zetterberg H, Rowe JB, Williams-Gray CH, Bryant CE, Klenerman D. Lobanova E, et al. Among authors: klenerman d. Nat Commun. 2024 Nov 11;15(1):9690. doi: 10.1038/s41467-024-53547-0. Nat Commun. 2024. PMID: 39528447 Free PMC article.
Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease.
Emin D, Zhang YP, Lobanova E, Miller A, Li X, Xia Z, Dakin H, Sideris DI, Lam JYL, Ranasinghe RT, Kouli A, Zhao Y, De S, Knowles TPJ, Vendruscolo M, Ruggeri FS, Aigbirhio FI, Williams-Gray CH, Klenerman D. Emin D, et al. Among authors: klenerman d. Nat Commun. 2022 Sep 20;13(1):5512. doi: 10.1038/s41467-022-33252-6. Nat Commun. 2022. PMID: 36127374 Free PMC article.
Improved Imaging Surface for Quantitative Single-Molecule Microscopy.
Zhang YP, Lobanova E, Dworkin A, Furlepa M, Yang WS, Burke M, Meng JX, Potter N, Sala RL, Kahanawita L, Layburn F, Scherman OA, Williams-Gray CH, Klenerman D. Zhang YP, et al. Among authors: klenerman d. ACS Appl Mater Interfaces. 2024 Jul 17;16(28):37255-37264. doi: 10.1021/acsami.4c06512. Epub 2024 Jul 9. ACS Appl Mater Interfaces. 2024. PMID: 38979642 Free PMC article.
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression.
De S, Whiten DR, Ruggeri FS, Hughes C, Rodrigues M, Sideris DI, Taylor CG, Aprile FA, Muyldermans S, Knowles TPJ, Vendruscolo M, Bryant C, Blennow K, Skoog I, Kern S, Zetterberg H, Klenerman D. De S, et al. Among authors: klenerman d. Acta Neuropathol Commun. 2019 Jul 26;7(1):120. doi: 10.1186/s40478-019-0777-4. Acta Neuropathol Commun. 2019. PMID: 31349874 Free PMC article.
An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patients.
Kulenkampff K, Emin D, Staats R, Zhang YP, Sakhnini L, Kouli A, Rimon O, Lobanova E, Williams-Gray CH, Aprile FA, Sormanni P, Klenerman D, Vendruscolo M. Kulenkampff K, et al. Among authors: klenerman d. Chem Sci. 2022 Sep 22;13(46):13815-13828. doi: 10.1039/d2sc00066k. eCollection 2022 Nov 30. Chem Sci. 2022. PMID: 36544716 Free PMC article.
272 results