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Page 1
A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV regulation.
Bertran MT, Walmsley R, Cummings T, Aramburu IV, Benton DJ, Mora Molina R, Assalaarachchi J, Chasampalioti M, Swanton T, Joshi D, Federico S, Okkenhaug H, Yu L, Oxley D, Walker S, Papayannopoulos V, Suga H, Christophorou MA, Walport LJ. Bertran MT, et al. Among authors: joshi d. Nat Commun. 2024 Nov 11;15(1):9746. doi: 10.1038/s41467-024-53554-1. Nat Commun. 2024. PMID: 39528459 Free PMC article.
Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α.
Ismail M, Martin SR, George R, Houghton F, Kelly G, Chaleil RAG, Anastasiou P, Wang X, O'Reilly N, Federico S, Joshi D, Nagaraj H, Cooley R, Hui NS, Molina-Arcas M, Hancock DC, Tavassoli A, Downward J. Ismail M, et al. Among authors: joshi d. Sci Rep. 2023 Feb 2;13(1):1889. doi: 10.1038/s41598-023-28756-0. Sci Rep. 2023. PMID: 36732563 Free PMC article.
O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern.
Gonzalez-Rodriguez E, Zol-Hanlon M, Bineva-Todd G, Marchesi A, Skehel M, Mahoney KE, Roustan C, Borg A, Di Vagno L, Kjær S, Wrobel AG, Benton DJ, Nawrath P, Flitsch SL, Joshi D, González-Ramírez AM, Wilkinson KA, Wilkinson RJ, Wall EC, Hurtado-Guerrero R, Malaker SA, Schumann B. Gonzalez-Rodriguez E, et al. Among authors: joshi d. ACS Cent Sci. 2023 Feb 16;9(3):393-404. doi: 10.1021/acscentsci.2c01349. eCollection 2023 Mar 22. ACS Cent Sci. 2023. PMID: 36968546 Free PMC article.
Glypicans shield the Wnt lipid moiety to enable signalling at a distance.
McGough IJ, Vecchia L, Bishop B, Malinauskas T, Beckett K, Joshi D, O'Reilly N, Siebold C, Jones EY, Vincent JP. McGough IJ, et al. Among authors: joshi d. Nature. 2020 Sep;585(7823):85-90. doi: 10.1038/s41586-020-2498-z. Epub 2020 Jul 22. Nature. 2020. PMID: 32699409 Free PMC article.
Preexisting and de novo humoral immunity to SARS-CoV-2 in humans.
Ng KW, Faulkner N, Cornish GH, Rosa A, Harvey R, Hussain S, Ulferts R, Earl C, Wrobel AG, Benton DJ, Roustan C, Bolland W, Thompson R, Agua-Doce A, Hobson P, Heaney J, Rickman H, Paraskevopoulou S, Houlihan CF, Thomson K, Sanchez E, Shin GY, Spyer MJ, Joshi D, O'Reilly N, Walker PA, Kjaer S, Riddell A, Moore C, Jebson BR, Wilkinson M, Marshall LR, Rosser EC, Radziszewska A, Peckham H, Ciurtin C, Wedderburn LR, Beale R, Swanton C, Gandhi S, Stockinger B, McCauley J, Gamblin SJ, McCoy LE, Cherepanov P, Nastouli E, Kassiotis G. Ng KW, et al. Among authors: joshi d. Science. 2020 Dec 11;370(6522):1339-1343. doi: 10.1126/science.abe1107. Epub 2020 Nov 6. Science. 2020. PMID: 33159009 Free PMC article.
1,224 results