Kappler R - Search Results

1

Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma.

Demir S, Hotes A, Schmid T, Cairo S, Indersie E, Pisano C, Hiyama E, Hishiki T, Vokuhl C, Branchereau S, Brock P, Schmid I, Zsiros J, Kappler R. Demir S, et al. Among authors: kappler r. J Exp Clin Cancer Res. 2024 Nov 12;43(1):299. doi: 10.1186/s13046-024-03221-6. J Exp Clin Cancer Res. 2024. PMID: 39529166 Free PMC article.

2

Targeting G9a/DNMT1 methyltransferase activity impedes IGF2-mediated survival in hepatoblastoma.

Demir S, Razizadeh N, Indersie E, Branchereau S, Cairo S, Kappler R. Demir S, et al. Among authors: kappler r. Hepatol Commun. 2024 Jan 29;8(2):e0378. doi: 10.1097/HC9.0000000000000378. eCollection 2024 Feb 1. Hepatol Commun. 2024. PMID: 38285887 Free PMC article.

3

MicroRNA-492 is processed from the keratin 19 gene and up-regulated in metastatic hepatoblastoma.

von Frowein J, Pagel P, Kappler R, von Schweinitz D, Roscher A, Schmid I. von Frowein J, et al. Among authors: kappler r. Hepatology. 2011 Mar;53(3):833-42. doi: 10.1002/hep.24125. Epub 2011 Feb 11. Hepatology. 2011. PMID: 21319197

4

Connectivity map identifies HDAC inhibition as a treatment option of high-risk hepatoblastoma.

Beck A, Eberherr C, Hagemann M, Cairo S, Häberle B, Vokuhl C, von Schweinitz D, Kappler R. Beck A, et al. Among authors: kappler r. Cancer Biol Ther. 2016 Nov;17(11):1168-1176. doi: 10.1080/15384047.2016.1235664. Epub 2016 Sep 16. Cancer Biol Ther. 2016. PMID: 27635950 Free PMC article.

5

MiR-492 regulates metastatic properties of hepatoblastoma via CD44.

von Frowein J, Hauck SM, Kappler R, Pagel P, Fleischmann KK, Magg T, Cairo S, Roscher A, von Schweinitz D, Schmid I. von Frowein J, et al. Among authors: kappler r. Liver Int. 2018 Jul;38(7):1280-1291. doi: 10.1111/liv.13687. Epub 2018 Jan 25. Liver Int. 2018. PMID: 29314711

6

A combined clinical and biological risk classification improves prediction of outcome in hepatoblastoma patients.

Cairo S, Armengol C, Maibach R, Häberle B, Becker K, Carrillo-Reixach J, Guettier C, Vokuhl C, Schmid I, Buendia MA, Branchereau S, von Schweinitz D, Kappler R. Cairo S, et al. Among authors: kappler r. Eur J Cancer. 2020 Dec;141:30-39. doi: 10.1016/j.ejca.2020.09.026. Epub 2020 Oct 27. Eur J Cancer. 2020. PMID: 33125945 Free article.

7

Targeting the Unwindosome by Mebendazole Is a Vulnerability of Chemoresistant Hepatoblastoma.

Li Q, Demir S, Del Río-Álvarez Á, Maxwell R, Wagner A, Carrillo-Reixach J, Armengol C, Vokuhl C, Häberle B, von Schweinitz D, Schmid I, Cairo S, Kappler R. Li Q, et al. Among authors: kappler r. Cancers (Basel). 2022 Aug 30;14(17):4196. doi: 10.3390/cancers14174196. Cancers (Basel). 2022. PMID: 36077733 Free PMC article.

8

Computational drug prediction in hepatoblastoma by integrating pan-cancer transcriptomics with pharmacological response.

Failli M, Demir S, Del Río-Álvarez Á, Carrillo-Reixach J, Royo L, Domingo-Sàbat M, Childs M, Maibach R, Alaggio R, Czauderna P, Morland B, Branchereau S, Cairo S, Kappler R, Armengol C, di Bernardo D. Failli M, et al. Among authors: kappler r. Hepatology. 2024 Jul 1;80(1):55-68. doi: 10.1097/HEP.0000000000000601. Epub 2023 Sep 20. Hepatology. 2024. PMID: 37729391 Free PMC article.

9

Establishing a three-dimensional scaffold model of hepatoblastoma.

Weigl EJ, Demir S, Schmid T, Hotes A, Muensterer O, Kappler R. Weigl EJ, et al. Among authors: kappler r. Front Bioeng Biotechnol. 2023 Nov 23;11:1229490. doi: 10.3389/fbioe.2023.1229490. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 38076431 Free PMC article.

10

Downregulation of SFRP1 is a protumorigenic event in hepatoblastoma and correlates with beta-catenin mutations.

Regel I, Eichenmüller M, Mahajan UM, Hagl B, Benitz S, Häberle B, Vokuhl C, von Schweinitz D, Kappler R. Regel I, et al. Among authors: kappler r. J Cancer Res Clin Oncol. 2020 May;146(5):1153-1167. doi: 10.1007/s00432-020-03182-1. Epub 2020 Mar 18. J Cancer Res Clin Oncol. 2020. PMID: 32189106 Free PMC article.

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