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USP1 deubiquitinates PARP1 to regulate its trapping and PARylation activity.
Nespolo A, Stefenatti L, Pellarin I, Gambelli A, Rampioni Vinciguerra GL, Karimbayli J, Barozzi S, Orsenigo F, Spizzo R, Nicoloso MS, Segatto I, D'Andrea S, Bartoletti M, Lucia E, Giorda G, Canzonieri V, Puglisi F, Belletti B, Schiappacassi M, Baldassarre G, Sonego M. Nespolo A, et al. Among authors: sonego m. Sci Adv. 2024 Nov 15;10(46):eadp6567. doi: 10.1126/sciadv.adp6567. Epub 2024 Nov 13. Sci Adv. 2024. PMID: 39536107 Free PMC article.
USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability.
Sonego M, Pellarin I, Costa A, Vinciguerra GLR, Coan M, Kraut A, D'Andrea S, Dall'Acqua A, Castillo-Tong DC, Califano D, Losito S, Spizzo R, Couté Y, Vecchione A, Belletti B, Schiappacassi M, Baldassarre G. Sonego M, et al. Sci Adv. 2019 May 8;5(5):eaav3235. doi: 10.1126/sciadv.aav3235. eCollection 2019 May. Sci Adv. 2019. PMID: 31086816 Free PMC article.
Platinum-induced upregulation of ITGA6 promotes chemoresistance and spreading in ovarian cancer.
Gambelli A, Nespolo A, Rampioni Vinciguerra GL, Pivetta E, Pellarin I, Nicoloso MS, Scapin C, Stefenatti L, Segatto I, Favero A, D'Andrea S, Mucignat MT, Bartoletti M, Lucia E, Schiappacassi M, Spessotto P, Canzonieri V, Giorda G, Puglisi F, Vecchione A, Belletti B, Sonego M, Baldassarre G. Gambelli A, et al. Among authors: sonego m. EMBO Mol Med. 2024 May;16(5):1162-1192. doi: 10.1038/s44321-024-00069-3. Epub 2024 Apr 24. EMBO Mol Med. 2024. PMID: 38658801 Free PMC article.
Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.
Sonego M, Schiappacassi M, Lovisa S, Dall'Acqua A, Bagnoli M, Lovat F, Libra M, D'Andrea S, Canzonieri V, Militello L, Napoli M, Giorda G, Pivetta B, Mezzanzanica D, Barbareschi M, Valeri B, Canevari S, Colombatti A, Belletti B, Del Sal G, Baldassarre G. Sonego M, et al. EMBO Mol Med. 2013 May;5(5):707-22. doi: 10.1002/emmm.201201504. Epub 2013 Apr 22. EMBO Mol Med. 2013. PMID: 23610071 Free PMC article.
CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation.
Dall'Acqua A, Sonego M, Pellizzari I, Pellarin I, Canzonieri V, D'Andrea S, Benevol S, Sorio R, Giorda G, Califano D, Bagnoli M, Militello L, Mezzanzanica D, Chiappetta G, Armenia J, Belletti B, Schiappacassi M, Baldassarre G. Dall'Acqua A, et al. Among authors: sonego m. EMBO Mol Med. 2017 Oct;9(10):1415-1433. doi: 10.15252/emmm.201607012. EMBO Mol Med. 2017. PMID: 28778953 Free PMC article.
Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells.
Ranzuglia V, Lorenzon I, Pellarin I, Sonego M, Dall'Acqua A, D'Andrea S, Lovisa S, Segatto I, Coan M, Polesel J, Serraino D, Sabatelli P, Spessotto P, Belletti B, Baldassarre G, Schiappacassi M. Ranzuglia V, et al. Among authors: sonego m. Oncogene. 2020 Oct;39(40):6370-6386. doi: 10.1038/s41388-020-01433-6. Epub 2020 Aug 27. Oncogene. 2020. PMID: 32848212 Free PMC article.
82 results