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Concizumab improves clot formation in hemophilia A under flow.
Jewell MP, Ashour Z, Baird CH, Manco Johnson M, Warren BB, Wufsus AR, Pallini C, Dockal M, Kjalke M, Neeves KB. Jewell MP, et al. Among authors: kjalke m. J Thromb Haemost. 2024 Sep;22(9):2438-2448. doi: 10.1016/j.jtha.2024.05.020. Epub 2024 May 28. J Thromb Haemost. 2024. PMID: 38815755
Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets.
Enoksson M, Martin EJ, Holmberg H, Jensen MS, Kjelgaard-Hansen M, Egebjerg T, Buchardt J, Krogh TN, Demuth H, Sanfridson A, Hilden I, Kjalke M, Brophy DF. Enoksson M, et al. Among authors: kjalke m. J Thromb Haemost. 2020 Jan;18(1):104-113. doi: 10.1111/jth.14644. Epub 2019 Oct 14. J Thromb Haemost. 2020. PMID: 31549480 Free article.
A novel next-generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys.
Lauritzen B, Bjelke M, Björkdahl O, Bloem E, Keane K, Kjalke M, Rossen M, Lippert SL, Weldingh KN, Skydsgaard M, Kjellev S. Lauritzen B, et al. Among authors: kjalke m. J Thromb Haemost. 2022 Jun;20(6):1312-1324. doi: 10.1111/jth.15682. Epub 2022 Mar 6. J Thromb Haemost. 2022. PMID: 35191180 Free PMC article.
Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8-GP) and development of a human pharmacokinetic prediction model.
Rode F, Almholt K, Petersen M, Kreilgaard M, Kjalke M, Karpf DM, Groth AV, Johansen PB, Larsen LF, Loftager M, Haaning J. Rode F, et al. Among authors: kjalke m. J Thromb Haemost. 2018 Jun;16(6):1141-1152. doi: 10.1111/jth.14013. Epub 2018 May 10. J Thromb Haemost. 2018. PMID: 29582559 Free article.
44 results