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Targeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling.
Brewer A, Zhao JF, Fasimoye R, Shpiro N, Macartney TJ, Wood NT, Wightman M, Alessi DR, Sapkota GP. Brewer A, et al. Among authors: sapkota gp. iScience. 2024 Jul 5;27(8):110423. doi: 10.1016/j.isci.2024.110423. eCollection 2024 Aug 16. iScience. 2024. PMID: 39104417 Free PMC article.
Targeted dephosphorylation of TFEB promotes its nuclear translocation.
Zhao JF, Shpiro N, Sathe G, Brewer A, Macartney TJ, Wood NT, Negoita F, Sakamoto K, Sapkota GP. Zhao JF, et al. Among authors: sapkota gp. iScience. 2024 Jun 29;27(8):110432. doi: 10.1016/j.isci.2024.110432. eCollection 2024 Aug 16. iScience. 2024. PMID: 39081292 Free PMC article.
Proteomic approaches advancing targeted protein degradation.
Sathe G, Sapkota GP. Sathe G, et al. Among authors: sapkota gp. Trends Pharmacol Sci. 2023 Nov;44(11):786-801. doi: 10.1016/j.tips.2023.08.007. Epub 2023 Sep 29. Trends Pharmacol Sci. 2023. PMID: 37778939 Free article. Review.
The promise of targeted protein degradation approaches.
Daniels DL, Sapkota GP, Jones LH. Daniels DL, et al. Among authors: sapkota gp. Trends Pharmacol Sci. 2023 Nov;44(11):746-749. doi: 10.1016/j.tips.2023.08.015. Epub 2023 Sep 28. Trends Pharmacol Sci. 2023. PMID: 37775456 No abstract available.
75 results