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919 results

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Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ.
Kiourtis C, Terradas-Terradas M, Gee LM, May S, Georgakopoulou A, Collins AL, O'Sullivan ED, Baird DP, Hassan M, Shaw R, Tan EH, Müller M, Engelmann C, Andreola F, Hsieh YC, Reed LH, Borthwick LA, Nixon C, Clark W, Hanson PS, Sumpton D, Mackay G, Suzuki T, Najumudeen AK, Inman GJ, Campbell A, Barry ST, Quaglia A, Morris CM, LeBeau FEN, Sansom OJ, Kirschner K, Jalan R, Oakley F, Bird TG. Kiourtis C, et al. Among authors: hsieh yc. Nat Cell Biol. 2024 Dec;26(12):2075-2083. doi: 10.1038/s41556-024-01543-3. Epub 2024 Nov 13. Nat Cell Biol. 2024. PMID: 39537753 Free PMC article.
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.
Dawson A, Zarou MM, Prasad B, Bittencourt-Silvestre J, Zerbst D, Himonas E, Hsieh YC, van Loon I, Blanco GR, Ianniciello A, Kerekes Z, Krishnan V, Agarwal P, Almasoudi H, McCluskey L, Hopcroft LEM, Scott MT, Baquero P, Dunn K, Vetrie D, Copland M, Bhatia R, Coffelt SB, Tiong OS, Wheadon H, Zanivan S, Kirschner K, Helgason GV. Dawson A, et al. Among authors: hsieh yc. Nat Commun. 2024 Feb 5;15(1):1090. doi: 10.1038/s41467-024-45471-0. Nat Commun. 2024. PMID: 38316788 Free PMC article.
An investigation of targeted inhibition of transcription factor activity with pyrrole imidazole polyamide (PA) in chronic myeloid leukemia (CML) blast crisis cells.
Hayatigolkhatmi K, Padroni G, Su W, Fang L, Gómez-Castañeda E, Hsieh YC, Jackson L, Pellicano F, Burley GA, Jørgensen HG. Hayatigolkhatmi K, et al. Among authors: hsieh yc. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2622-2625. doi: 10.1016/j.bmcl.2019.07.049. Epub 2019 Jul 27. Bioorg Med Chem Lett. 2019. PMID: 31378570 Free article.
Investigation of a minor groove-binding polyamide targeted to E2F1 transcription factor in chronic myeloid leukaemia (CML) cells.
Hayatigolkhatmi K, Padroni G, Su W, Fang L, Gómez-Castañeda E, Hsieh YC, Jackson L, Holyoake TL, Pellicano F, Burley GA, Jørgensen HG. Hayatigolkhatmi K, et al. Among authors: hsieh yc. Blood Cells Mol Dis. 2018 Mar;69:119-122. doi: 10.1016/j.bcmd.2017.11.002. Epub 2017 Nov 26. Blood Cells Mol Dis. 2018. PMID: 29217295 Free article. No abstract available.
919 results