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Page 1
Effect of NFX-179 MEK inhibitor on cutaneous neurofibromas in persons with neurofibromatosis type 1.
Sarin KY, Bradshaw M, O'Mara C, Shahryari J, Kincaid J, Kempers S, Tu JH, Dhawan S, DuBois J, Wilson D, Horwath P, de Souza MP, Powala C, Kochendoerfer GG, Plotkin SR, Webster GF, Le LQ. Sarin KY, et al. Among authors: kochendoerfer gg. Sci Adv. 2024 May 3;10(18):eadk4946. doi: 10.1126/sciadv.adk4946. Epub 2024 May 1. Sci Adv. 2024. PMID: 38691597 Free PMC article. Clinical Trial.
Development of a MEK inhibitor, NFX-179, as a chemoprevention agent for squamous cell carcinoma.
Sarin KY, Kincaid J, Sell B, Shahryari J, Duncton MAJ, Morefield E, Sun W, Prieto K, Chavez-Chiang O, de Moran Segura C, Nguyen J, Bronson RT, Plotkin SR, Kochendoerfer GG, Fenn P, Wootton MA, Powala C, de Souza MP, Tsai KY. Sarin KY, et al. Among authors: kochendoerfer gg. Sci Transl Med. 2023 Oct 11;15(717):eade1844. doi: 10.1126/scitranslmed.ade1844. Epub 2023 Oct 11. Sci Transl Med. 2023. PMID: 37820007
A chemical approach to the pharmaceutical optimization of an anti-HIV protein.
Miranda LP, Shao H, Williams J, Chen SY, Kong T, Garcia R, Chinn Y, Fraud N, O'Dwyer B, Ye J, Wilken J, Low DE, Cagle EN, Carnevali M, Lee A, Song D, Kung A, Bradburne JA, Paliard X, Kochendoerfer GG. Miranda LP, et al. Among authors: kochendoerfer gg. J Am Chem Soc. 2007 Oct 31;129(43):13153-9. doi: 10.1021/ja073982h. Epub 2007 Oct 4. J Am Chem Soc. 2007. PMID: 17915868
Synthetic erythropoietic proteins: tuning biological performance by site-specific polymer attachment.
Chen SY, Cressman S, Mao F, Shao H, Low DW, Beilan HS, Cagle EN, Carnevali M, Gueriguian V, Keogh PJ, Porter H, Stratton SM, Wiedeke MC, Savatski L, Adamson JW, Bozzini CE, Kung A, Kent SB, Bradburne JA, Kochendoerfer GG. Chen SY, et al. Among authors: kochendoerfer gg. Chem Biol. 2005 Mar;12(3):371-83. doi: 10.1016/j.chembiol.2005.01.017. Chem Biol. 2005. PMID: 15797221
Site-specific polymer attachment to a CCL-5 (RANTES) analogue by oxime exchange.
Shao H, Crnogorac MM, Kong T, Chen SY, Williams JM, Tack JM, Gueriguian V, Cagle EN, Carnevali M, Tumelty D, Paliard X, Miranda LP, Bradburne JA, Kochendoerfer GG. Shao H, et al. Among authors: kochendoerfer gg. J Am Chem Soc. 2005 Feb 9;127(5):1350-1. doi: 10.1021/ja043096w. J Am Chem Soc. 2005. PMID: 15686348
24 results