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High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum.
Johannsen S, Gierse RM, Krüger A, Edwards RL, Nanna V, Fontana A, Zhu D, Masini T, de Carvalho LP, Poizat M, Kieftenbelt B, Hodge DM, Alvarez S, Bunt D, Lacour A, Shams A, Meissner KA, de Souza EE, Dröge M, van Vliet B, den Hartog J, Hutter MC, Held J, Odom John AR, Wrenger C, Hirsch AKH. Johannsen S, et al. Among authors: de carvalho lp. ACS Infect Dis. 2024 Mar 8;10(3):1000-1022. doi: 10.1021/acsinfecdis.3c00670. Epub 2024 Feb 17. ACS Infect Dis. 2024. PMID: 38367280 Free PMC article.
Targeting the Plasmodium falciparum IspE Enzyme.
Diamanti E, Steinbach AM, de Carvalho LP, Ropponen HK, Lacour A, Hamid R, Eisa S, Bravo P, Bousis S, Illarionov B, Fischer M, Hamed MM, Bach NC, Rottmann M, Held J, Witschel M, Sieber SA, Hirsch AKH. Diamanti E, et al. Among authors: de carvalho lp. ACS Omega. 2024 Oct 25;9(44):44465-44473. doi: 10.1021/acsomega.4c06038. eCollection 2024 Nov 5. ACS Omega. 2024. PMID: 39524657 Free PMC article.
Lesional senescent CD4+ T cells mediate bystander cytolysis and contribute to the skin pathology of human cutaneous leishmaniasis.
Covre LP, Fantecelle CH, Garcia de Moura R, Oliveira Lopes P, Sarmento IV, Freire-de-Lima CG, Decote-Ricardo D, de Matos Guedes HL, da Fonsceca-Martins AM, de Carvalho LP, de Carvalho EM, Mosser DM, Falqueto A, Akbar AN, Gomes DCO. Covre LP, et al. Among authors: de carvalho lp. Front Immunol. 2024 Oct 21;15:1475146. doi: 10.3389/fimmu.2024.1475146. eCollection 2024. Front Immunol. 2024. PMID: 39497830 Free PMC article.
Plasma ceramides as biomarkers for microvascular disease and clinical outcomes in diabetes and myocardial infarction.
Junqueira DL, Cavalcanti AB, Sallum JMF, Yasaki E, de Andrade Jesuíno I, Stach A, Negrelli K, de Oliveira Silva L, Lopes MA, Caixeta A, Chan MY, Ching J, Carvalho VM, Faccio AT, Tsutsui J, Rizzatti E, Fonseca RA, Summers S, Fonseca HA, Rochitte CE, Krieger JE, de Carvalho LP. Junqueira DL, et al. Among authors: de carvalho lp. Clin Diabetes Endocrinol. 2024 Sep 17;10(1):32. doi: 10.1186/s40842-024-00186-5. Clin Diabetes Endocrinol. 2024. PMID: 39285502 Free PMC article.
Editorial overview: emerging avenues in antimicrobial research.
Gabaldón T, de Carvalho LPS. Gabaldón T, et al. Among authors: de carvalho lps. Curr Opin Microbiol. 2024 Oct;81:102522. doi: 10.1016/j.mib.2024.102522. Epub 2024 Aug 7. Curr Opin Microbiol. 2024. PMID: 39116668 No abstract available.
156 results