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Page 1
Molecular Heterogeneity and Immune Infiltration Drive Clinical Outcomes in Upper Tract Urothelial Carcinoma.
Kim K, Alam SM, Kuo F, Chen Z, Yip W, Katims AB, Chu C, Lenis AT, Hu W, Gokturk Ozcan G, Chen JF, Firouzi S, Elhanati Y, Clinton TN, Aulitzky A, Almassi N, Fujii Y, Tracey AT, Reisz PA, Budhu S, Vuong L, Eichholz J, Woo HJ, Nogueira L, Gao SP, Scherz A, Aggen DH, Rosenberg JE, Pietzak EJ, Seshan V, Greenbaum B, Becker A, Akin O, Iyer G, Al-Ahmadie H, Hakimi AA, Merghoub T, Solit DB, Coleman JA. Kim K, et al. Among authors: hu w. Eur Urol. 2024 Nov 15:S0302-2838(24)02686-1. doi: 10.1016/j.eururo.2024.10.024. Online ahead of print. Eur Urol. 2024. PMID: 39550333 Free article.
Genomic Differences Between "Primary" and "Secondary" Muscle-invasive Bladder Cancer as a Basis for Disparate Outcomes to Cisplatin-based Neoadjuvant Chemotherapy.
Pietzak EJ, Zabor EC, Bagrodia A, Armenia J, Hu W, Zehir A, Funt S, Audenet F, Barron D, Maamouri N, Li Q, Teo MY, Arcila ME, Berger MF, Schultz N, Dalbagni G, Herr HW, Bajorin DF, Rosenberg JE, Al-Ahmadie H, Bochner BH, Solit DB, Iyer G. Pietzak EJ, et al. Among authors: hu w. Eur Urol. 2019 Feb;75(2):231-239. doi: 10.1016/j.eururo.2018.09.002. Epub 2018 Oct 2. Eur Urol. 2019. PMID: 30290956 Free PMC article.
Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts.
Kim K, Hu W, Audenet F, Almassi N, Hanrahan AJ, Murray K, Bagrodia A, Wong N, Clinton TN, Dason S, Mohan V, Jebiwott S, Nagar K, Gao J, Penson A, Hughes C, Gordon B, Chen Z, Dong Y, Watson PA, Alvim R, Elzein A, Gao SP, Cocco E, Santin AD, Ostrovnaya I, Hsieh JJ, Sagi I, Pietzak EJ, Hakimi AA, Rosenberg JE, Iyer G, Vargas HA, Scaltriti M, Al-Ahmadie H, Solit DB, Coleman JA. Kim K, et al. Among authors: hu w. Nat Commun. 2020 Apr 24;11(1):1975. doi: 10.1038/s41467-020-15885-7. Nat Commun. 2020. PMID: 32332851 Free PMC article.
FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation.
Warrick JI, Hu W, Yamashita H, Walter V, Shuman L, Craig JM, Gellert LL, Castro MAA, Robertson AG, Kuo F, Ostrovnaya I, Sarungbam J, Chen YB, Gopalan A, Sirintrapun SJ, Fine SW, Tickoo SK, Kim K, Thomas J, Karan N, Gao SP, Clinton TN, Lenis AT, Chan TA, Chen Z, Rao M, Hollman TJ, Li Y, Socci ND, Chavan S, Viale A, Mohibullah N, Bochner BH, Pietzak EJ, Teo MY, Iyer G, Rosenberg JE, Bajorin DF, Kaag M, Merrill SB, Joshi M, Adam R, Taylor JA 3rd, Clark PE, Raman JD, Reuter VE, Chen Y, Funt SA, Solit DB, DeGraff DJ, Al-Ahmadie HA. Warrick JI, et al. Among authors: hu w. Nat Commun. 2022 Nov 2;13(1):6575. doi: 10.1038/s41467-022-34251-3. Nat Commun. 2022. PMID: 36323682 Free PMC article.
Genomic heterogeneity as a barrier to precision oncology in urothelial cancer.
Clinton TN, Chen Z, Wise H, Lenis AT, Chavan S, Donoghue MTA, Almassi N, Chu CE, Dason S, Rao P, Rodrigues JA, Vasani NB, Ridouani F, Rosenberg JE, Bajorin DF, Teo MY, Bochner BH, Berger MF, Ostrovnaya I, Pietzak EJ, Iyer G, Gao SP, Hu W, Al-Ahmadie HA, Solit DB. Clinton TN, et al. Among authors: hu w. Cell Rep. 2022 Dec 20;41(12):111859. doi: 10.1016/j.celrep.2022.111859. Cell Rep. 2022. PMID: 36543146 Free PMC article.
Genomic landscape of inverted urothelial papilloma and urothelial papilloma of the bladder.
Isharwal S, Hu W, Sarungbam J, Chen YB, Gopalan A, Fine SW, Tickoo SK, Sirintrapun SJ, Jadallah S, Loo FL, Pietzak EJ, Cha EK, Bochner BH, Berger MF, Iyer G, Solit DB, Reuter VE, Al-Ahmadie H. Isharwal S, et al. Among authors: hu w. J Pathol. 2019 Jul;248(3):260-265. doi: 10.1002/path.5261. Epub 2019 Apr 22. J Pathol. 2019. PMID: 30838648 Free PMC article.
Author Correction: FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation.
Warrick JI, Hu W, Yamashita H, Walter V, Shuman L, Craig JM, Gellert LL, Castro MAA, Robertson AG, Kuo F, Ostrovnaya I, Sarungbam J, Chen YB, Gopalan A, Sirintrapun SJ, Fine SW, Tickoo SK, Kim K, Thomas J, Karan N, Gao SP, Clinton TN, Lenis AT, Chan TA, Chen Z, Rao M, Hollman TJ, Li Y, Socci ND, Chavan S, Viale A, Mohibullah N, Bochner BH, Pietzak EJ, Teo MY, Iyer G, Rosenberg JE, Bajorin DF, Kaag M, Merrill SB, Joshi M, Adam R, Taylor JA 3rd, Clark PE, Raman JD, Reuter VE, Chen Y, Funt SA, Solit DB, DeGraff DJ, Al-Ahmadie HA. Warrick JI, et al. Among authors: hu w. Nat Commun. 2022 Dec 23;13(1):7920. doi: 10.1038/s41467-022-35644-0. Nat Commun. 2022. PMID: 36564410 Free PMC article. No abstract available.
Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer.
Lee SH, Hu W, Matulay JT, Silva MV, Owczarek TB, Kim K, Chua CW, Barlow LJ, Kandoth C, Williams AB, Bergren SK, Pietzak EJ, Anderson CB, Benson MC, Coleman JA, Taylor BS, Abate-Shen C, McKiernan JM, Al-Ahmadie H, Solit DB, Shen MM. Lee SH, et al. Among authors: hu w. Cell. 2018 Apr 5;173(2):515-528.e17. doi: 10.1016/j.cell.2018.03.017. Cell. 2018. PMID: 29625057 Free PMC article.
AKT1 E17K Inhibits Cancer Cell Migration by Abrogating β-Catenin Signaling.
Gao SP, Kiliti AJ, Zhang K, Vasani N, Mao N, Jordan E, Wise HC, Shrestha Bhattarai T, Hu W, Dorso M, Rodrigues JA, Kim K, Hanrahan AJ, Razavi P, Carver B, Chandarlapaty S, Reis-Filho JS, Taylor BS, Solit DB. Gao SP, et al. Among authors: hu w. Mol Cancer Res. 2021 Apr;19(4):573-584. doi: 10.1158/1541-7786.MCR-20-0623. Epub 2020 Dec 10. Mol Cancer Res. 2021. PMID: 33303690 Free PMC article.
Leveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer.
Hanrahan AJ, Sylvester BE, Chang MT, Elzein A, Gao J, Han W, Liu Y, Xu D, Gao SP, Gorelick AN, Jones AM, Kiliti AJ, Nissan MH, Nimura CA, Poteshman AN, Yao Z, Gao Y, Hu W, Wise HC, Gavrila EI, Shoushtari AN, Tiwari S, Viale A, Abdel-Wahab O, Merghoub T, Berger MF, Rosen N, Taylor BS, Solit DB. Hanrahan AJ, et al. Among authors: hu w. Cancer Res. 2020 Oct 1;80(19):4233-4243. doi: 10.1158/0008-5472.CAN-20-0865. Epub 2020 Jul 8. Cancer Res. 2020. PMID: 32641410 Free PMC article.
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