Leroux MR - Search Results

1

C. elegans PPEF-type phosphatase (Retinal degeneration C ortholog) functions in diverse classes of cilia to regulate nematode behaviors.

Barbelanne M, Lu Y, Kumar K, Zhang X, Li C, Park K, Warner A, Xu XZS, Shaham S, Leroux MR. Barbelanne M, et al. Among authors: leroux mr. Sci Rep. 2024 Nov 16;14(1):28347. doi: 10.1038/s41598-024-79057-z. Sci Rep. 2024. PMID: 39550471 Free PMC article.

2

The Caenorhabditis elegans Shugoshin regulates TAC-1 in cilia.

Reed R, Park K, Waddell B, Timbers TA, Li C, Baxi K, Giacomin RM, Leroux MR, Carvalho CE. Reed R, et al. Among authors: leroux mr. Sci Rep. 2023 Jun 9;13(1):9410. doi: 10.1038/s41598-023-36430-8. Sci Rep. 2023. PMID: 37296204 Free PMC article.

3

Functional genomics of the cilium, a sensory organelle.

Blacque OE, Perens EA, Boroevich KA, Inglis PN, Li C, Warner A, Khattra J, Holt RA, Ou G, Mah AK, McKay SJ, Huang P, Swoboda P, Jones SJ, Marra MA, Baillie DL, Moerman DG, Shaham S, Leroux MR. Blacque OE, et al. Among authors: leroux mr. Curr Biol. 2005 May 24;15(10):935-41. doi: 10.1016/j.cub.2005.04.059. Curr Biol. 2005. PMID: 15916950 Free article.

4

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

Canning P, Park K, Gonçalves J, Li C, Howard CJ, Sharpe TD, Holt LJ, Pelletier L, Bullock AN, Leroux MR. Canning P, et al. Among authors: leroux mr. Cell Rep. 2018 Jan 23;22(4):885-894. doi: 10.1016/j.celrep.2017.12.083. Epub 2018 Jan 28. Cell Rep. 2018. PMID: 29420175 Free PMC article.

5

Role for intraflagellar transport in building a functional transition zone.

Jensen VL, Lambacher NJ, Li C, Mohan S, Williams CL, Inglis PN, Yoder BK, Blacque OE, Leroux MR. Jensen VL, et al. Among authors: leroux mr. EMBO Rep. 2018 Dec;19(12):e45862. doi: 10.15252/embr.201845862. Epub 2018 Nov 14. EMBO Rep. 2018. PMID: 30429209 Free PMC article.

6

EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling.

Loucks CM, Park K, Walker DS, McEwan AH, Timbers TA, Ardiel EL, Grundy LJ, Li C, Johnson JL, Kennedy J, Blacque OE, Schafer W, Rankin CH, Leroux MR. Loucks CM, et al. Among authors: leroux mr. Elife. 2019 Feb 27;8:e37271. doi: 10.7554/eLife.37271. Elife. 2019. PMID: 30810526 Free PMC article.

7

CDKL kinase regulates the length of the ciliary proximal segment.

Park K, Li C, Tsiropoulou S, Gonçalves J, Kondratev C, Pelletier L, Blacque OE, Leroux MR. Park K, et al. Among authors: leroux mr. Curr Biol. 2021 Jun 7;31(11):2359-2373.e7. doi: 10.1016/j.cub.2021.03.068. Epub 2021 Apr 14. Curr Biol. 2021. PMID: 33857430 Free article.

8

IFT trains overcome an NPHP module barrier at the transition zone.

Park K, Leroux MR. Park K, et al. Among authors: leroux mr. J Cell Biol. 2022 Jan 3;221(1):e202112015. doi: 10.1083/jcb.202112015. Epub 2021 Dec 10. J Cell Biol. 2022. PMID: 34889953 Free PMC article.

9

Composition, organization and mechanisms of the transition zone, a gate for the cilium.

Park K, Leroux MR. Park K, et al. Among authors: leroux mr. EMBO Rep. 2022 Dec 6;23(12):e55420. doi: 10.15252/embr.202255420. Epub 2022 Nov 21. EMBO Rep. 2022. PMID: 36408840 Free PMC article. Review.

10

Formation of the transition zone by Mks5/Rpgrip1L establishes a ciliary zone of exclusion (CIZE) that compartmentalises ciliary signalling proteins and controls PIP2 ciliary abundance.

Jensen VL, Li C, Bowie RV, Clarke L, Mohan S, Blacque OE, Leroux MR. Jensen VL, et al. Among authors: leroux mr. EMBO J. 2015 Oct 14;34(20):2537-56. doi: 10.15252/embj.201488044. Epub 2015 Sep 21. EMBO J. 2015. PMID: 26392567 Free PMC article.

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