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Mesenchymal stromal cell apoptosis is required for their therapeutic function.
Pang SHM, D'Rozario J, Mendonca S, Bhuvan T, Payne NL, Zheng D, Hisana A, Wallis G, Barugahare A, Powell D, Rautela J, Huntington ND, Dewson G, Huang DCS, Gray DHD, Heng TSP. Pang SHM, et al. Among authors: heng tsp. Nat Commun. 2021 Nov 11;12(1):6495. doi: 10.1038/s41467-021-26834-3. Nat Commun. 2021. PMID: 34764248 Free PMC article.
Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages.
D'Rozario J, Knoblich K, Lütge M, Shibayama CP, Cheng HW, Alexandre YO, Roberts D, Campos J, Dutton EE, Suliman M, Denton AE, Turley SJ, Boyd RL, Mueller SN, Ludewig B, Heng TSP, Fletcher AL. D'Rozario J, et al. Among authors: heng tsp. Eur J Immunol. 2023 Sep;53(9):e2250355. doi: 10.1002/eji.202250355. Epub 2023 Jul 12. Eur J Immunol. 2023. PMID: 36991561 Free PMC article.
Lymph node stroma join the cancer support network.
Fletcher AL, Heng TS. Fletcher AL, et al. Cell Death Differ. 2016 Dec;23(12):1899-1901. doi: 10.1038/cdd.2016.103. Epub 2016 Sep 30. Cell Death Differ. 2016. PMID: 27689877 Free PMC article. No abstract available.
Stem cells--meet immunity.
Heng TS, Dudakov JA, Khong DM, Chidgey AP, Boyd RL. Heng TS, et al. J Mol Med (Berl). 2009 Nov;87(11):1061-9. doi: 10.1007/s00109-009-0539-z. Epub 2009 Oct 16. J Mol Med (Berl). 2009. PMID: 19841876 Review.
22 results