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Markov Field network model of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques.
Wang S, Myers AJ, Irvine EB, Wang C, Maiello P, Rodgers MA, Tomko J, Kracinovsky K, Borish HJ, Chao MC, Mugahid D, Darrah PA, Seder RA, Roederer M, Scanga CA, Lin PL, Alter G, Fortune SM, Flynn JL, Lauffenburger DA. Wang S, et al. Among authors: myers aj. bioRxiv [Preprint]. 2024 Oct 30:2024.04.13.589359. doi: 10.1101/2024.04.13.589359. bioRxiv. 2024. Update in: Cell Syst. 2024 Dec 18;15(12):1278-1294.e4. doi: 10.1016/j.cels.2024.10.001 PMID: 39554028 Free PMC article. Updated. Preprint.
CD4 T cells and CD8α+ lymphocytes are necessary for intravenous BCG-induced protection against tuberculosis in macaques.
Simonson AW, Zeppa JJ, Bucsan AN, Chao MC, Pokkali S, Hopkins F, Chase MR, Vickers AJ, Sutton MS, Winchell CG, Myers AJ, Ameel CL, Kelly R, Krouse B, Hood LE, Li J, Lehman CC, Kamath M, Tomko J, Rodgers MA, Donlan R, Chishti H, Jacob Borish H, Klein E, Scanga CA, Fortune S, Lin PL, Maiello P, Roederer M, Darrah PA, Seder RA, Flynn JL. Simonson AW, et al. Among authors: myers aj. bioRxiv [Preprint]. 2024 May 17:2024.05.14.594183. doi: 10.1101/2024.05.14.594183. bioRxiv. 2024. PMID: 38798646 Free PMC article. Preprint.
Markov field network model of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques.
Wang S, Myers AJ, Irvine EB, Wang C, Maiello P, Rodgers MA, Tomko J, Kracinovsky K, Borish HJ, Chao MC, Mugahid D, Darrah PA, Seder RA, Roederer M, Scanga CA, Lin PL, Alter G, Fortune SM, Flynn JL, Lauffenburger DA. Wang S, et al. Among authors: myers aj. Cell Syst. 2024 Dec 18;15(12):1278-1294.e4. doi: 10.1016/j.cels.2024.10.001. Epub 2024 Nov 5. Cell Syst. 2024. PMID: 39504969 Free article.
Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques.
Darrah PA, DiFazio RM, Maiello P, Gideon HP, Myers AJ, Rodgers MA, Hackney JA, Lindenstrom T, Evans T, Scanga CA, Prikhodko V, Andersen P, Lin PL, Laddy D, Roederer M, Seder RA, Flynn JL. Darrah PA, et al. Among authors: myers aj. NPJ Vaccines. 2019 May 28;4:21. doi: 10.1038/s41541-019-0113-9. eCollection 2019. NPJ Vaccines. 2019. PMID: 31149352 Free PMC article.
CD8+ lymphocytes are critical for early control of tuberculosis in macaques.
Winchell CG, Nyquist SK, Chao MC, Maiello P, Myers AJ, Hopkins F, Chase M, Gideon HP, Patel KV, Bromley JD, Simonson AW, Floyd-O'Sullivan R, Wadsworth M, Rosenberg JM, Uddin R, Hughes T, Kelly RJ, Griffo J, Tomko J, Klein E, Berger B, Scanga CA, Mattila J, Fortune SM, Shalek AK, Lin PL, Flynn JL. Winchell CG, et al. Among authors: myers aj. J Exp Med. 2023 Dec 4;220(12):e20230707. doi: 10.1084/jem.20230707. Epub 2023 Oct 16. J Exp Med. 2023. PMID: 37843832 Free PMC article.
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.
Gideon HP, Phuah J, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL. Gideon HP, et al. Among authors: myers aj. PLoS Pathog. 2015 Jan 22;11(1):e1004603. doi: 10.1371/journal.ppat.1004603. eCollection 2015 Jan. PLoS Pathog. 2015. PMID: 25611466 Free PMC article.
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control.
Gideon HP, Hughes TK, Tzouanas CN, Wadsworth MH 2nd, Tu AA, Gierahn TM, Peters JM, Hopkins FF, Wei JR, Kummerlowe C, Grant NL, Nargan K, Phuah JY, Borish HJ, Maiello P, White AG, Winchell CG, Nyquist SK, Ganchua SKC, Myers A, Patel KV, Ameel CL, Cochran CT, Ibrahim S, Tomko JA, Frye LJ, Rosenberg JM, Shih A, Chao M, Klein E, Scanga CA, Ordovas-Montanes J, Berger B, Mattila JT, Madansein R, Love JC, Lin PL, Leslie A, Behar SM, Bryson B, Flynn JL, Fortune SM, Shalek AK. Gideon HP, et al. Immunity. 2022 May 10;55(5):827-846.e10. doi: 10.1016/j.immuni.2022.04.004. Epub 2022 Apr 27. Immunity. 2022. PMID: 35483355 Free PMC article.
160 results