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Page 1
Molecular basis for chemokine recognition and activation of XCR1.
Zhang X, Schlimgen RR, Singh S, Tomani MP, Volkman BF, Zhang C. Zhang X, et al. Among authors: schlimgen rr. Proc Natl Acad Sci U S A. 2024 Nov 26;121(48):e2405732121. doi: 10.1073/pnas.2405732121. Epub 2024 Nov 20. Proc Natl Acad Sci U S A. 2024. PMID: 39565315
The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist.
Berg C, Wedemeyer MJ, Melynis M, Schlimgen RR, Hansen LH, Våbenø J, Peterson FC, Volkman BF, Rosenkilde MM, Lüttichau HR. Berg C, et al. Among authors: schlimgen rr. PLoS Pathog. 2022 Mar 10;18(3):e1010355. doi: 10.1371/journal.ppat.1010355. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35271688 Free PMC article.
Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.
Perez Almeria CV, Otun O, Schlimgen R, Lamme TD, Crudden C, Youssef N, Musli L, Jenjak S, Bobkov V, Drube J, Hoffmann C, Volkman BF, Granier S, Bechara C, Siderius M, Heukers R, Schafer CT, Smit MJ. Perez Almeria CV, et al. bioRxiv [Preprint]. 2024 Nov 4:2024.11.04.621790. doi: 10.1101/2024.11.04.621790. bioRxiv. 2024. PMID: 39574661 Free PMC article. Preprint.