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MTBVAC induces superior antibody titers and IgG avidity compared to BCG vaccination in non-human primates.
Peralta-Álvarez MP, Downward K, White A, Redondo Azema H, Sibley L, Sarfas C, Morrison A, Dennis M, Diaz-Santana D, Harris SA, Li S, Puentes E, Aguilo N, Martin C, Sharpe S, McShane H, Tanner R. Peralta-Álvarez MP, et al. Among authors: dennis m. NPJ Vaccines. 2024 Nov 20;9(1):230. doi: 10.1038/s41541-024-01009-5. NPJ Vaccines. 2024. PMID: 39567530 Free PMC article.
MTBVAC vaccination protects rhesus macaques against aerosol challenge with M. tuberculosis and induces immune signatures analogous to those observed in clinical studies.
White AD, Sibley L, Sarfas C, Morrison A, Gullick J, Clark S, Gleeson F, McIntyre A, Arlehamn CL, Sette A, Salguero FJ, Rayner E, Rodriguez E, Puentes E, Laddy D, Williams A, Dennis M, Martin C, Sharpe S. White AD, et al. Among authors: dennis m. NPJ Vaccines. 2021 Jan 4;6(1):4. doi: 10.1038/s41541-020-00262-8. NPJ Vaccines. 2021. PMID: 33397991 Free PMC article.
Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates.
Peralta Alvarez MP, Jones H, Redondo Azema H, Davis C, White AD, Sarfas C, Dennis M, Li S, Wright D, Puentes E, Kimuda S, Belij-Rammerstorfer S, Aguilo N, Martin C, Sharpe S, McShane H, Tanner R. Peralta Alvarez MP, et al. Among authors: dennis m. Front Immunol. 2024 May 10;15:1387454. doi: 10.3389/fimmu.2024.1387454. eCollection 2024. Front Immunol. 2024. PMID: 38799468 Free PMC article.
Intravenous BCG vaccination in non-human primates induces superior serum antibody titers with enhanced avidity and opsonizing capacity compared to the intradermal route.
Peralta Alvarez MP, Downward K, White A, Harris SA, Satti I, Li S, Morrison A, Sibley L, Sarfas C, Dennis M, Azema HR, Sharpe S, McShane H, Tanner R. Peralta Alvarez MP, et al. Among authors: dennis m. Vaccine. 2024 Dec 2;42(26):126444. doi: 10.1016/j.vaccine.2024.126444. Epub 2024 Nov 10. Vaccine. 2024. PMID: 39522337 Free article.
Evaluation of the safety and immunogenicity of a candidate tuberculosis vaccine, MVA85A, delivered by aerosol to the lungs of macaques.
White AD, Sibley L, Dennis MJ, Gooch K, Betts G, Edwards N, Reyes-Sandoval A, Carroll MW, Williams A, Marsh PD, McShane H, Sharpe SA. White AD, et al. Among authors: dennis mj. Clin Vaccine Immunol. 2013 May;20(5):663-72. doi: 10.1128/CVI.00690-12. Epub 2013 Feb 27. Clin Vaccine Immunol. 2013. PMID: 23446219 Free PMC article.
2,189 results