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RECQL4 affects MHC class II-mediated signalling and favours an immune-evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma.
Egea-Rodriguez S, Váraljai R, Nordmann TM, Lubis R, Philip M, Rambow F, Roesch A, Flaig M, Horn S, Stoll R, Zhao F, Paschen A, Klebl B, Hickson ID, Schadendorf D, Mann M, Helfrich I. Egea-Rodriguez S, et al. Among authors: zhao f. Clin Transl Med. 2025 Jan;15(1):e70094. doi: 10.1002/ctm2.70094. Clin Transl Med. 2025. PMID: 39812592
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