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Page 1
DNA repair and anti-cancer mechanisms in the long-lived bowhead whale.
Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, Lu JY, Zheng Z, Perelli L, Gurreri E, Zhang L, Guo J, Korotkov A, Volobaev V, Biashad SA, Zhang Z, Heid J, Maslov A, Sun S, Wu Z, Gigas J, Hillpot E, Martinez J, Lee M, Williams A, Gilman A, Hamilton N, Haseljic E, Patel A, Straight M, Miller N, Ablaeva J, Tam LM, Couderc C, Hoopman M, Moritz R, Fujii S, Hayman DJ, Liu H, Cai Y, Leung AKL, Simons MJP, Zhang Z, Nelson CB, Abegglen LM, Schiffman JD, Gladyshev VN, Modesti M, Genovese G, Vijg J, Seluanov A, Gorbunova V. Firsanov D, et al. Among authors: hillpot e. bioRxiv [Preprint]. 2024 Nov 5:2023.05.07.539748. doi: 10.1101/2023.05.07.539748. bioRxiv. 2024. PMID: 39574710 Free PMC article. Preprint.
cGAS deficient mice display premature aging associated with de-repression of LINE1 elements and inflammation.
Martinez JC, Morandini F, Fitzgibbons L, Sieczkiewicz N, Bae SJ, Meadow ME, Hillpot E, Cutting J, Paige V, Biashad SA, Simon M, Sedivy J, Seluanov A, Gorbunova V. Martinez JC, et al. Among authors: hillpot e. bioRxiv [Preprint]. 2024 Oct 11:2024.10.10.617645. doi: 10.1101/2024.10.10.617645. bioRxiv. 2024. PMID: 39416083 Free PMC article. Preprint.
Evolution of High-Molecular-Mass Hyaluronic Acid is Associated with Subterranean Lifestyle.
Zhao Y, Zheng Z, Zhang Z, Hillpot E, Lin YS, Zakusilo FT, Lu JY, Ablaeva J, Miller RA, Nevo E, Seluanov A, Gorbunova V. Zhao Y, et al. Among authors: hillpot e. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539764. doi: 10.1101/2023.05.08.539764. bioRxiv. 2023. Update in: Nat Commun. 2023 Dec 5;14(1):8054. doi: 10.1038/s41467-023-43623-2 PMID: 37215017 Free PMC article. Updated. Preprint.
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: hillpot e. EMBO J. 2023 Feb 1;42(3):e113326. doi: 10.15252/embj.2022113326. EMBO J. 2023. PMID: 36722290 Free PMC article.
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Thomas DD, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: hillpot e. EMBO J. 2022 Nov 2;41(21):e110393. doi: 10.15252/embj.2021110393. Epub 2022 Oct 10. EMBO J. 2022. PMID: 36215696 Free PMC article.