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Page 1
Harnessing IL-22 for metabolic health: promise and pitfalls.
Sajiir H, Ramm GA, Macdonald GA, McGuckin MA, Prins JB, Hasnain SZ. Sajiir H, et al. Among authors: mcguckin ma. Trends Mol Med. 2024 Nov 21:S1471-4914(24)00283-1. doi: 10.1016/j.molmed.2024.10.016. Online ahead of print. Trends Mol Med. 2024. PMID: 39578121 Free article. Review.
Interleukin-22 suppresses major histocompatibility complex II in mucosal epithelial cells.
Moniruzzaman M, Rahman MA, Wang R, Wong KY, Chen AC, Mueller A, Taylor S, Harding A, Illankoon T, Wiid P, Sajiir H, Schreiber V, Burr LD, McGuckin MA, Phipps S, Hasnain SZ. Moniruzzaman M, et al. Among authors: mcguckin ma. J Exp Med. 2023 Nov 6;220(11):e20230106. doi: 10.1084/jem.20230106. Epub 2023 Sep 11. J Exp Med. 2023. PMID: 37695525 Free PMC article.
Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis.
Sajiir H, Keshvari S, Wong KY, Borg DJ, Steyn FJ, Fercher C, Taylor K, Taylor B, Barnard RT, Müller A, Moniruzzaman M, Miller G, Wang R, Fotheringham A, Schreiber V, Sheng YH, Hancock JL, Loo D, Burr L, Huynh T, Lockett J, Ramm GA, Macdonald GA, Prins JB, McGuckin MA, Hasnain SZ. Sajiir H, et al. Among authors: mcguckin ma. Nat Commun. 2024 May 29;15(1):4528. doi: 10.1038/s41467-024-48317-x. Nat Commun. 2024. PMID: 38811532 Free PMC article.
Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis.
Sajiir H, Wong KY, Müller A, Keshvari S, Burr L, Aiello E, Mezza T, Giaccari A, Sebastiani G, Dotta F, Ramm GA, Macdonald GA, McGuckin MA, Prins JB, Hasnain SZ. Sajiir H, et al. Among authors: mcguckin ma. Nat Commun. 2024 May 29;15(1):4527. doi: 10.1038/s41467-024-48320-2. Nat Commun. 2024. PMID: 38811550 Free PMC article.
Goblet cells as mucosal sentinels for immunity.
McGuckin MA, Hasnain SZ. McGuckin MA, et al. Mucosal Immunol. 2017 Sep;10(5):1118-1121. doi: 10.1038/mi.2016.132. Epub 2017 Jan 25. Mucosal Immunol. 2017. PMID: 28120847 Free article. No abstract available.
MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial Barrier.
McGuckin MA, Davies JM, Felgner P, Wong KY, Giri R, He Y, Moniruzzaman M, Kryza T, Sajiir H, Hooper JD, Florin TH, Begun J, Oussalah A, Hasnain SZ, Hensel M, Sheng YH. McGuckin MA, et al. Cell Mol Gastroenterol Hepatol. 2023;16(6):985-1009. doi: 10.1016/j.jcmgh.2023.08.011. Epub 2023 Sep 1. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37660948 Free PMC article.
There is a 'uc' in mucus, but is there mucus in UC?
McGuckin MA, Hasnain SZ. McGuckin MA, et al. Gut. 2014 Feb;63(2):216-7. doi: 10.1136/gutjnl-2013-304602. Epub 2013 Apr 17. Gut. 2014. PMID: 23595349 No abstract available.
164 results