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Harnessing IL-22 for metabolic health: promise and pitfalls.
Sajiir H, Ramm GA, Macdonald GA, McGuckin MA, Prins JB, Hasnain SZ. Sajiir H, et al. Among authors: prins jb. Trends Mol Med. 2024 Nov 21:S1471-4914(24)00283-1. doi: 10.1016/j.molmed.2024.10.016. Online ahead of print. Trends Mol Med. 2024. PMID: 39578121 Free article. Review.
Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis.
Sajiir H, Keshvari S, Wong KY, Borg DJ, Steyn FJ, Fercher C, Taylor K, Taylor B, Barnard RT, Müller A, Moniruzzaman M, Miller G, Wang R, Fotheringham A, Schreiber V, Sheng YH, Hancock JL, Loo D, Burr L, Huynh T, Lockett J, Ramm GA, Macdonald GA, Prins JB, McGuckin MA, Hasnain SZ. Sajiir H, et al. Among authors: prins jb. Nat Commun. 2024 May 29;15(1):4528. doi: 10.1038/s41467-024-48317-x. Nat Commun. 2024. PMID: 38811532 Free PMC article.
Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis.
Sajiir H, Wong KY, Müller A, Keshvari S, Burr L, Aiello E, Mezza T, Giaccari A, Sebastiani G, Dotta F, Ramm GA, Macdonald GA, McGuckin MA, Prins JB, Hasnain SZ. Sajiir H, et al. Among authors: prins jb. Nat Commun. 2024 May 29;15(1):4527. doi: 10.1038/s41467-024-48320-2. Nat Commun. 2024. PMID: 38811550 Free PMC article.
Resveratrol does not benefit patients with nonalcoholic fatty liver disease.
Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Chachay VS, et al. Among authors: prins jb. Clin Gastroenterol Hepatol. 2014 Dec;12(12):2092-103.e1-6. doi: 10.1016/j.cgh.2014.02.024. Epub 2014 Feb 25. Clin Gastroenterol Hepatol. 2014. PMID: 24582567 Clinical Trial.
347 results