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Matrix stiffness drives drop like nuclear deformation and lamin A/C tension-dependent YAP nuclear localization.
Wang TC, Abolghasemzade S, McKee BP, Singh I, Pendyala K, Mohajeri M, Patel H, Shaji A, Kersey AL, Harsh K, Kaur S, Dollahon CR, Chukkapalli S, Lele PP, Conway DE, Gaharwar AK, Dickinson RB, Lele TP. Wang TC, et al. Among authors: dollahon cr. Nat Commun. 2024 Nov 22;15(1):10151. doi: 10.1038/s41467-024-54577-4. Nat Commun. 2024. PMID: 39578439 Free PMC article.
Extreme wrinkling of the nuclear lamina is a morphological marker of cancer.
Wang TC, Dollahon CR, Mishra S, Patel H, Abolghasemzade S, Singh I, Thomazy V, Rosen DG, Sandulache VC, Chakraborty S, Lele TP. Wang TC, et al. Among authors: dollahon cr. NPJ Precis Oncol. 2024 Dec 2;8(1):276. doi: 10.1038/s41698-024-00775-8. NPJ Precis Oncol. 2024. PMID: 39623008 Free PMC article.