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Extreme wrinkling of the nuclear lamina is a morphological marker of cancer.
Wang TC, Dollahon CR, Mishra S, Patel H, Abolghasemzade S, Singh I, Thomazy V, Rosen DG, Sandulache VC, Chakraborty S, Lele TP. Wang TC, et al. Among authors: lele tp. NPJ Precis Oncol. 2024 Dec 2;8(1):276. doi: 10.1038/s41698-024-00775-8. NPJ Precis Oncol. 2024. PMID: 39623008 Free PMC article.
Matrix stiffness drives drop like nuclear deformation and lamin A/C tension-dependent YAP nuclear localization.
Wang TC, Abolghasemzade S, McKee BP, Singh I, Pendyala K, Mohajeri M, Patel H, Shaji A, Kersey AL, Harsh K, Kaur S, Dollahon CR, Chukkapalli S, Lele PP, Conway DE, Gaharwar AK, Dickinson RB, Lele TP. Wang TC, et al. Among authors: lele tp. Nat Commun. 2024 Nov 22;15(1):10151. doi: 10.1038/s41467-024-54577-4. Nat Commun. 2024. PMID: 39578439 Free PMC article.
Genetic variation drives cancer cell adaptation to ECM stiffness.
Wang TC, Sawhney S, Morgan D, Bennett RL, Rashmi R, Estecio MR, Brock A, Singh I, Baer CF, Licht JD, Lele TP. Wang TC, et al. Among authors: lele tp. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2403062121. doi: 10.1073/pnas.2403062121. Epub 2024 Sep 20. Proc Natl Acad Sci U S A. 2024. PMID: 39302966 Free PMC article.
Editorial: Nuclear morphology in development and disease.
Lele TP, Levy DL, Mishra K. Lele TP, et al. Front Cell Dev Biol. 2023 Aug 8;11:1267645. doi: 10.3389/fcell.2023.1267645. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37614225 Free PMC article. No abstract available.
85 results