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Strategies to reduce the risks of mRNA drug and vaccine toxicity.
Bitounis D, Jacquinet E, Rogers MA, Amiji MM. Bitounis D, et al. Among authors: jacquinet e. Nat Rev Drug Discov. 2024 Apr;23(4):281-300. doi: 10.1038/s41573-023-00859-3. Epub 2024 Jan 23. Nat Rev Drug Discov. 2024. PMID: 38263456 Review.
Intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 infection.
Baldeon Vaca G, Meyer M, Cadete A, Hsiao CJ, Golding A, Jeon A, Jacquinet E, Azcue E, Guan CM, Sanchez-Felix X, Pietzsch CA, Mire CE, Hyde MA, Comeaux ME, Williams JM, Sung JC, Carfi A, Edwards DK, Bukreyev A, Bahl K. Baldeon Vaca G, et al. Among authors: jacquinet e. Sci Adv. 2023 Sep 22;9(38):eadh1655. doi: 10.1126/sciadv.adh1655. Epub 2023 Sep 22. Sci Adv. 2023. PMID: 37738334 Free PMC article.
Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia.
Jiang L, Park JS, Yin L, Laureano R, Jacquinet E, Yang J, Liang S, Frassetto A, Zhuo J, Yan X, Zhu X, Fortucci S, Hoar K, Mihai C, Tunkey C, Presnyak V, Benenato KE, Lukacs CM, Martini PGV, Guey LT. Jiang L, et al. Among authors: jacquinet e. Nat Commun. 2020 Oct 21;11(1):5339. doi: 10.1038/s41467-020-19156-3. Nat Commun. 2020. PMID: 33087718 Free PMC article.
Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines.
Hassett KJ, Benenato KE, Jacquinet E, Lee A, Woods A, Yuzhakov O, Himansu S, Deterling J, Geilich BM, Ketova T, Mihai C, Lynn A, McFadyen I, Moore MJ, Senn JJ, Stanton MG, Almarsson Ö, Ciaramella G, Brito LA. Hassett KJ, et al. Among authors: jacquinet e. Mol Ther Nucleic Acids. 2019 Apr 15;15:1-11. doi: 10.1016/j.omtn.2019.01.013. Epub 2019 Feb 7. Mol Ther Nucleic Acids. 2019. PMID: 30785039 Free PMC article.
16 results