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Role of type 2 ryanodine receptor stabilisation in autoimmune cell modulation.
Nawata T, Honda T, Sakamoto A, Uchinoumi H, Suetomi T, Nakamura Y, Tsuji S, Sakai H, Kobayashi S, Yamamoto T, Asagiri M, Sano M, Yano M. Nawata T, et al. Among authors: nakamura y. Adv Rheumatol. 2024 Nov 22;64(1):86. doi: 10.1186/s42358-024-00426-3. Adv Rheumatol. 2024. PMID: 39578889 No abstract available.
Stabilizing cardiac ryanodine receptor with dantrolene treatment prevents left ventricular remodeling in pressure-overloaded heart failure mice.
Yano Y, Kobayashi S, Uchida T, Chang Y, Nawata J, Fujii S, Nakamura Y, Suetomi T, Uchinoumi H, Oda T, Yamamoto T, Yano M. Yano Y, et al. Among authors: nakamura y. Biochem Biophys Res Commun. 2023 Jan 29;642:175-184. doi: 10.1016/j.bbrc.2022.12.063. Epub 2022 Dec 22. Biochem Biophys Res Commun. 2023. PMID: 36584481
Nuclear translocation of calmodulin in pathological cardiac hypertrophy originates from ryanodine receptor bound calmodulin.
Oda T, Yamamoto T, Kato T, Uchinoumi H, Fukui G, Hamada Y, Nanno T, Ishiguchi H, Nakamura Y, Okamoto Y, Kono M, Okuda S, Kobayashi S, Bers DM, Yano M. Oda T, et al. Among authors: nakamura y. J Mol Cell Cardiol. 2018 Dec;125:87-97. doi: 10.1016/j.yjmcc.2018.10.011. Epub 2018 Oct 22. J Mol Cell Cardiol. 2018. PMID: 30359562 Free PMC article.
Dantrolene prevents ventricular tachycardia by stabilizing the ryanodine receptor in pressure- overload induced failing hearts.
Kajii T, Kobayashi S, Shiba S, Fujii S, Tamitani M, Kohno M, Nakamura Y, Nanno T, Kato T, Okuda S, Uchinoumi H, Oda T, Yamamoto T, Yano M. Kajii T, et al. Among authors: nakamura y. Biochem Biophys Res Commun. 2020 Jan 1;521(1):57-63. doi: 10.1016/j.bbrc.2019.10.071. Epub 2019 Oct 18. Biochem Biophys Res Commun. 2020. PMID: 31635807
Stabilization of RyR2 maintains right ventricular function, reduces the development of ventricular arrhythmias, and improves prognosis in pulmonary hypertension.
Tanaka S, Yamamoto T, Mikawa M, Nawata J, Fujii S, Nakamura Y, Kato T, Fukuda M, Suetomi T, Uchinoumi H, Oda T, Okuda S, Okamura T, Kobayashi S, Yano M. Tanaka S, et al. Among authors: nakamura y. Heart Rhythm. 2022 Jun;19(6):986-997. doi: 10.1016/j.hrthm.2022.02.003. Epub 2022 Feb 5. Heart Rhythm. 2022. PMID: 35134547
Endoplasmic reticulum stress promotes nuclear translocation of calmodulin, which activates phenotypic switching of vascular smooth muscle cells.
Uchida T, Oda T, Yamamoto T, Inamitsu M, Sakai C, Uchinoumi H, Suetomi T, Nakamura Y, Okamoto Y, Tateda S, Fujii S, Tanaka S, Nawata J, Okamura T, Kobayashi S, Yano M. Uchida T, et al. Among authors: nakamura y. Biochem Biophys Res Commun. 2022 Nov 5;628:155-162. doi: 10.1016/j.bbrc.2022.08.069. Epub 2022 Aug 28. Biochem Biophys Res Commun. 2022. PMID: 36099691 Free article.
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