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946 results

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Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain.
Ikenuma H, Ogata A, Koyama H, Ji B, Ishii H, Yamada T, Abe J, Seki C, Nagai Y, Ichise M, Minamimoto T, Higuchi M, Zhang MR, Kato T, Ito K, Suzuki M, Kimura Y. Ikenuma H, et al. Among authors: abe j. EJNMMI Radiopharm Chem. 2023 Oct 18;8(1):31. doi: 10.1186/s41181-023-00217-z. EJNMMI Radiopharm Chem. 2023. PMID: 37853253 Free PMC article.
Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone.
Ikenuma H, Koyama H, Kajino N, Kimura Y, Ogata A, Abe J, Kawasumi Y, Kato T, Takashima A, Ito K, Suzuki M. Ikenuma H, et al. Among authors: abe j. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2107-2111. doi: 10.1016/j.bmcl.2019.07.005. Epub 2019 Jul 3. Bioorg Med Chem Lett. 2019. PMID: 31311732
Estimation of blood-based biomarkers of glial activation related to neuroinflammation.
Yasuno F, Watanabe A, Kimura Y, Yamauchi Y, Ogata A, Ikenuma H, Abe J, Minami H, Nihashi T, Yokoi K, Hattori S, Shimoda N, Kasuga K, Ikeuchi T, Takeda A, Sakurai T, Ito K, Kato T. Yasuno F, et al. Among authors: abe j. Brain Behav Immun Health. 2022 Nov 5;26:100549. doi: 10.1016/j.bbih.2022.100549. eCollection 2022 Dec. Brain Behav Immun Health. 2022. PMID: 36388135 Free PMC article.
Development of a novel PET ligand, [11C]GO289 targeting CK2 expressed in the brain.
Ogata A, Yamada T, Hattori S, Ikenuma H, Abe J, Tada M, Ichise M, Suzuki M, Ito K, Kato T, Amaike K, Hirota T, Kakita A, Itami K, Kimura Y. Ogata A, et al. Among authors: abe j. Bioorg Med Chem Lett. 2023 Jun 15;90:129327. doi: 10.1016/j.bmcl.2023.129327. Epub 2023 May 13. Bioorg Med Chem Lett. 2023. PMID: 37187253
Neuroimaging biomarkers of glial activation for predicting the annual cognitive function decline in patients with Alzheimer's disease.
Yasuno F, Kimura Y, Ogata A, Ikenuma H, Abe J, Minami H, Nihashi T, Yokoi K, Hattori S, Shimoda N, Watanabe A, Kasuga K, Ikeuchi T, Takeda A, Sakurai T, Ito K, Kato T. Yasuno F, et al. Among authors: abe j. Brain Behav Immun. 2023 Nov;114:214-220. doi: 10.1016/j.bbi.2023.08.027. Epub 2023 Aug 28. Brain Behav Immun. 2023. PMID: 37648003 Free article.
946 results