Blanco MR - Search Results

1

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements.

Perez AA, Goronzy IN, Blanco MR, Yeh BT, Guo JK, Lopes CS, Ettlin O, Burr A, Guttman M. Perez AA, et al. Among authors: blanco mr. Nat Genet. 2024 Dec;56(12):2827-2841. doi: 10.1038/s41588-024-02000-5. Epub 2024 Nov 25. Nat Genet. 2024. PMID: 39587360

2

Genome organization around nuclear speckles drives mRNA splicing efficiency.

Bhat P, Chow A, Emert B, Ettlin O, Quinodoz SA, Strehle M, Takei Y, Burr A, Goronzy IN, Chen AW, Huang W, Ferrer JLM, Soehalim E, Goh ST, Chari T, Sullivan DK, Blanco MR, Guttman M. Bhat P, et al. Among authors: blanco mr. Nature. 2024 May;629(8014):1165-1173. doi: 10.1038/s41586-024-07429-6. Epub 2024 May 8. Nature. 2024. PMID: 38720076 Free PMC article.

3

SPIDR: a highly multiplexed method for mapping RNA-protein interactions uncovers a potential mechanism for selective translational suppression upon cellular stress.

Wolin E, Guo JK, Blanco MR, Perez AA, Goronzy IN, Abdou AA, Gorhe D, Guttman M, Jovanovic M. Wolin E, et al. Among authors: blanco mr. bioRxiv [Preprint]. 2023 Jun 7:2023.06.05.543769. doi: 10.1101/2023.06.05.543769. bioRxiv. 2023. PMID: 37333139 Free PMC article. Preprint.

4

ChIP-DIP: A multiplexed method for mapping hundreds of proteins to DNA uncovers diverse regulatory elements controlling gene expression.

Perez AA, Goronzy IN, Blanco MR, Guo JK, Guttman M. Perez AA, et al. Among authors: blanco mr. bioRxiv [Preprint]. 2023 Dec 18:2023.12.14.571730. doi: 10.1101/2023.12.14.571730. bioRxiv. 2023. PMID: 38187704 Free PMC article. Preprint.

5

Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo.

Guo JK, Blanco MR, Walkup WG 4th, Bonesteele G, Urbinati CR, Banerjee AK, Chow A, Ettlin O, Strehle M, Peyda P, Amaya E, Trinh V, Guttman M. Guo JK, et al. Among authors: blanco mr. Mol Cell. 2024 Apr 4;84(7):1271-1289.e12. doi: 10.1016/j.molcel.2024.01.026. Epub 2024 Feb 21. Mol Cell. 2024. PMID: 38387462

6

Re-evaluating the foundations of lncRNA-Polycomb function.

Blanco MR, Guttman M. Blanco MR, et al. EMBO J. 2017 Apr 13;36(8):964-966. doi: 10.15252/embj.201796796. Epub 2017 Mar 15. EMBO J. 2017. PMID: 28298433 Free PMC article.

7

RNA promotes the formation of spatial compartments in the nucleus.

Quinodoz SA, Jachowicz JW, Bhat P, Ollikainen N, Banerjee AK, Goronzy IN, Blanco MR, Chovanec P, Chow A, Markaki Y, Thai J, Plath K, Guttman M. Quinodoz SA, et al. Among authors: blanco mr. Cell. 2021 Nov 11;184(23):5775-5790.e30. doi: 10.1016/j.cell.2021.10.014. Epub 2021 Nov 4. Cell. 2021. PMID: 34739832 Free PMC article.

8

Xist spatially amplifies SHARP/SPEN recruitment to balance chromosome-wide silencing and specificity to the X chromosome.

Jachowicz JW, Strehle M, Banerjee AK, Blanco MR, Thai J, Guttman M. Jachowicz JW, et al. Among authors: blanco mr. Nat Struct Mol Biol. 2022 Mar;29(3):239-249. doi: 10.1038/s41594-022-00739-1. Epub 2022 Mar 17. Nat Struct Mol Biol. 2022. PMID: 35301492 Free PMC article.

9

PRC2-RNA interactions: Viewpoint from Jimmy K. Guo, Mario R. Blanco, and Mitchell Guttman.

Guo JK, Blanco MR, Guttman M. Guo JK, et al. Among authors: blanco mr. Mol Cell. 2024 Oct 3;84(19):3578-3585. doi: 10.1016/j.molcel.2024.09.007. Mol Cell. 2024. PMID: 39366346

10

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M. McHugh CA, et al. Nature. 2015 May 14;521(7551):232-6. doi: 10.1038/nature14443. Epub 2015 Apr 27. Nature. 2015. PMID: 25915022 Free PMC article.

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